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Registry of Toxic Effects of Chemical Substances (RTECS)

Benzene, 1-chloro-2-(chloromethyl)-

RTECS #

CZ0195000

CAS #

611-19-8

Updated

November 2009

Molecular Weight

161.03

Molecular Formula

C7H6Cl2

Synonyms

1-Chloro-2-(chloromethyl)benzene
2-Chlorobenzyl chloride
alpha,2-Dichlorotoluene
alpha,o-Dichlorotoluene
o,alpha-Dichlorotoluene
o-Chlorobenzyl chloride
o-Chlorobenzylchloride
Toluene, alpha,o-dichloro- (8CI)

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): >1140 mg/m3/1HEPASR* 8EHQ-0990-1020
unreported route/rat lethal dose (50 percent kill): 430 mg/kgEPASR* 8EHQ-0990-1020

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
intravenous/guinea pig lowest published toxic dose: 0.24 mg/kg/12W- intermittentSkin: After systemic exposure: Dermatitis, allergic

Immunological Including Allergic: Hypersensitivity delayed (multiple organ involvement)
JEMEAV 64,625,1936

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWFCTOD7 47,1287,2009

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAtime-weighted average 0.5 mg/m3, short term exposure limit 1.5 mg/m3, Skin, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 84023; Number of Industries 1; Total Number of Facilities 21; Number of Occupations 5; Total Number of Employees Exposed 4354; Total Number of Female Employees Exposed 729
National Occupational Hazard Survey 1974Hazard Code 84023; Number of Industries 1; Total Number of Facilities 5; Number of Occupations 2; Total Number of Employees Exposed 20

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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