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Registry of Toxic Effects of Chemical Substances (RTECS)

Benzeneacetic acid, 4-chloro-alpha-(1-methylethyl)-, cyano (3-phenoxyphenyl)methyl ester,(S-(R*,R*))-

RTECS #

CY1576367

CAS #

66230-04-4; 72650-28-3

Updated

October 2010

Molecular Weight

419.93

Molecular Formula

C25H22ClNO3

Synonyms

(S)-alpha-Cyano-3-phenoxybenzyl(S)-2-(4-chlorophenyl)-3-methylbutyrate
Asana
Asana XL
Esfenvalerate
Fenvalerate A alpha
Fenvalerate alpha
Halmark
OMS 3023
S 1844
S 5602 A alpha
Sumi-alfa
Sumi-alpha
Sumicidin A alpha

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
unreported route/mammal (species unspecified) 5 mg/kg (multigenerations)Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
FEREAC 63,48609,1998

Tumorigenic Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 45600 mg/kg/2Y- continuousTumorigenic: Carcinogenic by RTECS criteriaFEREAC 63,48609,1998

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/mammal (species unspecified) lethal dose (50 percent kill): 87.2 mg/kgFEREAC 63,48609,1998
oral/rat lethal dose (50 percent kill): 325 mg/kgFMCHA2 -,C287,1991
oral/rat lowest published toxic dose: 0.48 mg/kgLiver: Other changes

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases
TOXID9 90,245,2006
skin/mammal (species unspecified) lethal dose (50 percent kill): 2000 mg/kgFEREAC 63,48609,1998
skin/rabbit lethal dose (50 percent kill): >2 gm/kgFMCHA2 -,C27,1991
skin/rat lethal dose (50 percent kill): >5 gm/kgFMCHA2 -,C287,1991
unreported route/rat lethal dose (50 percent kill): 95 mg/kgTOXID9 44,174,2005

Reviews

OrganizationStandardReference
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 53,309,1991
International Agency for Research on Cancer (IARC)Cancer Review:Human No Available DataIMEMDT 53,309,1991
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMEMDT 53,309,1991
TOXICOLOGY REVIEWFEREAC 73,80317,2008
TOXICOLOGY REVIEWFEREAC 74,12862,2009
TOXICOLOGY REVIEWFEREAC 74,46689,2009

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESActive registrationRBREV* -,368,1998

Status in Federal Agencies

OrganizationReference
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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