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Registry of Toxic Effects of Chemical Substances (RTECS)

Barium

RTECS #

CQ8370000

CAS #

7440-39-3

Updated

September 201

Molecular Weight

137.34

Molecular Formula

Ba

Synonyms

Barium (ACGIH:OSHA)

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/Dog lowest published lethal dose: 1 mg/kgBlood: Aplastic anemia

Blood: Changes in spleen
VCVN1* -,137,1988

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 26622 mg/kg/69W- continuousVascular: BP elevation not characterized in autonomic section

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)

Biochemical: Metabolism (intermediary): Xanthine, purine or nucleotides including urate
JTEHD6 28,373,1989

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.5 mg/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWTPHSDY 23,374,2002
TOXICOLOGY REVIEWENTOX* -,213,2005
TOXICOLOGY REVIEWJJATDK 26,191,2006
TOXICOLOGY REVIEWNTAPM* -,629,1995

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.5 mg/m3DTLVS* 3,21,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.5 mg/m3, JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 0.5 mg/m3;KZW 2 mg/m3, inhal, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 0.5 mg/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 mg(Ba)/m3, MAY2011
Occupational Exposure Limit-ICELANDtime-weighted average 0.5 mg(Ba)/m3, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 0.5 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.5 mg/m3, 2004
Occupational Exposure Limit-MEXICOtime-weighted average 0.5 mg(Ba)/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.5 mg/m3, JAN2002
Occupational Exposure Limit-PERUtime-weighted average 0.5 mg/m3, JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 0.5 mg/m3, MAC(short term exposure limit) 1.5 mg/m3, JAN1999
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.5 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.5 mg/m3, JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO BARIUM, soluble compounds-air10H time-weighted average 0.5 mg/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 08625; Number of Industries 15; Total Number of Facilities 901; Number of Occupations 64; Total Number of Employees Exposed 10394; Total Number of Female Employees Exposed 3598
National Occupational Hazard Survey 1974Hazard Code 08625; Number of Industries 13; Total Number of Facilities 657; Number of Occupations 31; Total Number of Employees Exposed 6101

Status in Federal Agencies

OrganizationReference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/93/110658/AS)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Barium, soluble compounds, 7056
NIOSH Analytical Method, 1994: Metals in urine, 8310
On EPA IRIS database
OSHA ANALYTICAL METHOD #ID121
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