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Barium

RTECS #: CQ8370000

CAS #: 7440-39-3


UPDATE: May 2009 MW: 137.34 MF: Ba


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Barium (ACGIH:OSHA)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
dog
lowest published lethal dose: 1 mg/kg Blood: Aplastic anemia

Blood: Changes in spleen
VCVN1* -,137,1988


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 26,622 mg/kg/69 week- continuous Vascular: BP elevation not characterized in autonomic section

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)

Biochemical: Metabolism (intermediary): Xanthine, purine or nucleotides including urate
JTEHD6 28,373,1989


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 mg/m3 DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as human carcinogen DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
TPHSDY 23,374,2002
TOXICOLOGY REVIEW
ENTOX* -,213,2005
TOXICOLOGY REVIEW
JJATDK 26,191,2006


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg/m3 DTLVS* 3,21,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.5 mg(Ba)/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 mg/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 mg/m3, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg(Ba)/m3, OCT 2002
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg/m3, OCT 2002
Occupational Exposure Limit - EC time-weighted average 0.5 mg/m3, FEB 2006
Occupational Exposure Limit - EC time-weighted average 0.5 mg(Ba)/m3, FEB 2006
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 mg/m3 (inhalable), 2005
Occupational Exposure Limit - GERMANY MAK 0.5 mg(Ba)/m3 (inhalable), 2005
Occupational Exposure Limit - KOREA time-weighted average 0.5 mg/m3, 2006
Occupational Exposure Limit - MEXICO time-weighted average 0.5 mg/m3, 2004
Occupational Exposure Limit - MEXICO time-weighted average 0.5 mg(Ba)/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.5 mg/m3, JAN2002
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.5 mg/m3, MAC(short term exposure limit) 1.5 mg/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 0.5 mg/m3;
KZG- week 1 mg/m3, DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.5 mg/m3, 2005
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.5 mg(Ba)/m3, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not classifiable as human carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not classifiable as human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO BARIUM, soluble compounds-air 10 hour time-weighted average 0.5 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 08625;
Number of Industries 13;
Total Number of Facilities 657;
Number of Occupations 31;
Total Number of Employees Exposed 6,101
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 08625;
Number of Industries 15;
Total Number of Facilities 901;
Number of Occupations 64;
Total Number of Employees Exposed 10,394;
Total Number of Female Employees Exposed 3,598


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

ATSDR TOXICOLOGY PROFILE (NTIS** PB/93/110658/AS)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Barium, soluble compounds, 7056
NIOSH Analytical Method, 1994: Metals in urine, 8310
OSHA ANALYTICAL METHOD #ID121


REFERENCES:

CODEN
REFERENCE

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TPHSDY Trends in Pharmacological Sciences. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1979-
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

NIOSH PROFILE (HEAVY METAL GREASES AND SOAPS), SRI, 2/77

NIOSH PROFILE (SMELTERS, SECONDARY NON-FERROUS), SRI, 2/77

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