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Registry of Toxic Effects of Chemical Substances (RTECS)

Antimony(III) chloride

RTECS #

CC4900000

CAS #

10025-91-9

Updated

September 201

Molecular Weight

228.10

Molecular Formula

Cl3Sb

Synonyms

Antimoine (trichlorure d') (French)
Antimonio (tricloruro di) (Italian)
Antimonous chloride
Antimontrichlorid (German)
Antimony butter
Antimony chloride (Sb2Cl6)
Antimony trichloride
Antimoontrichlride (Dutch)
Butter of antimony
C.I. 77056
Chlorid antimonity (Czech)
Chlorure antimonieux (French)
Stibine, trichloro-
Trichlorostibine
Trichlorure d'antimoine (French)

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
DNA repair/Bacillus subtilis10 mmol/LMUREAV 77,109,1980
micronucleus testlung/hamster10 µmol/LMUREAV 412,213,1998
sister chromatid exchangelung/hamster2500 µg/LMUREAV 264,163,1991

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
intramuscular/rat 1874 mg/kg (6-15D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)JANREH 10,15,1996
oral/rat 44 mg/kg (1-22D preg/22D after birth)Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)TCMUD8 7,491,1987
oral/rat 4400 µg/kg (1-22D preg/22D after birth)Reproductive: Effects on newborn: Delayed effectsTCMUD8 7,491,1987

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/human lowest published toxic concentration: 73 mg/m3Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Cough
HBTME* -,353,2007
inhalation/man lowest published toxic concentration: 73 mg/m3Behavioral: Anorexia (human)

Lung, Thorax, or Respiration: Other changes

Gastrointestinal: Other changes
BJIMAG 23,318,1966
intraperitoneal/mouse lethal dose (50 percent kill): 13 mg/kg85GMAT -,23,1982
oral/guinea pig lethal dose (50 percent kill): 574 mg/kgPeripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Gastrointestinal: Peritonitis

Gastrointestinal: Necrotic changes
HYSAAV 29(12),16,1964
oral/rat lethal dose (50 percent kill): 525 mg/kgMarJV# 29MAR1977

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/guinea pig lowest published toxic dose: 2282 mg/kg/9W- intermittentBlood: Pigmented or nucleated red blood cells

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Blood: Changes in other cell count (unspecified)
GISAAA 29(12),16,1964
oral/guinea pig lowest published toxic dose: 8518 mg/kg/26W- intermittentBlood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase
GISAAA 29(12),16,1964

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.5 mg(Sb)/m3DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWMUREAV 533,227,2003
TOXICOLOGY REVIEWHBTME* ,353,2007

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.5 mg(Sb)/m3DTLVS* 3,15,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-ARAB Republic of Egypttime-weighted average 0.5 mg(Sb)/m3, JAN1993
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.5 mg(Sb)/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.5 mg(Sb)/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 mg(Sb)/m3 (dust), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.5 mg(Sb)/m3, NOV2011
Occupational Exposure Limit-FRANCEVME 0.5 mg(Sb)/m3, FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 0.5 mg(Sb)/m3, short term exposure limit 2 mg(Sb)/m3, SEP2000
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.1 mg(Sb)/m3, MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 0.5 mg(Sb)/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.5 mg(Sb)/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.5 mg(Sb)/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.5 mg(Sb)/m3, JAN1999
Occupational Exposure Limit-POLANDMAC(time-weighted average) 0.5 mg(Sb)/m3, MAC(short term exposure limit) 1.5 mg(Sb)/m3, JAN1999
Occupational Exposure Limit-RUSSIAtime-weighted average 0.2 mg(Sb)/m3, short term exposure limit 0.5 mg(Sb)/m3, JUN2003
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.5 mg(Sb)/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.5 mg(Sb)/m3, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.5 mg(Sb)/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.5 mg(Sb)/m3, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.5 mg(Sb)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.5 mg(Sb)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.5 mg(Sb)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.5 mg(Sb)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ANTIMONY-air10H time-weighted average 0.5 mg(Sb)/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 07405; Number of Industries 9; Total Number of Facilities 344; Number of Occupations 11; Total Number of Employees Exposed 22641; Total Number of Female Employees Exposed 7292
National Occupational Hazard Survey 1974Hazard Code 07405; Number of Industries 6; Total Number of Facilities 125; Number of Occupations 9; Total Number of Employees Exposed 1947

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Positive: B subtilis rec assay
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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