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Aniline, 2,5 - dichloro -

RTECS #: BX2610000

CAS #: 95-82-9


UPDATE: October 1997 MW: 162.02 MF: C6H5Cl2N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 2,5 - Dichloranilin (Czech)
  2. 2,5 - Dichloroaniline
  3. 2,5 - Dichlorobenzenamine
  4. Amarthol Fast Scarlet GG Base
  5. Amarthol Fast Scarlet GGS Base
  6. Azobase DCA
  7. Azoene Fast Scarlet 2G Base
  8. Azogene Fast Scarlet GGC
  9. Azogene Fast Scarlet GG (free base)
  10. Azoic Diazo Component 3
  11. Benzenamine, 2,5 - dichloro - (9CI)
  12. C.I. 37010
  13. C.I. Azoic Diazo Component 3
  14. Daito Scarlet Base GG
  15. Devol Scarlet A (free base)
  16. Devol Scarlet 2GS Base
  17. Diazo Fast Scarlet GG
  18. Fast Red SGG Base
  19. Fast Scarlet Base ggt
  20. Fast Scarlet Base 2J
  21. Fast Scarlet Base 2JS
  22. Fast Scarlet DS Base
  23. Fast Scarlet 2G
  1. Fast Scarlet 2G Base
  2. Fast Scarlet GG Base
  3. Fast Scarlet GGS Base
  4. Fast Scarlet MDC Base
  5. Hiltonil Fast Scarlet 2G Base
  6. Hiltonil Fast Scarlet 2GS Base
  7. Hindamine Scarlet GG
  8. Kambamine Scarlet GG base
  9. Kayaku Scarlet GG Base
  10. Lake Scarlet GG Base
  11. Mitsui Scarlet GG base
  12. Naphthanil Scarlet 2G Base
  13. Naphtoelan Fast Scarlet GG Base
  14. Sanyo Fast Scarlet GG Base
  15. Scarlet Base Ciba I
  16. Scarlet Base GG
  17. Scarlet Base IRGA I (free base)
  18. Scarlet Base NGG
  19. Scarlet 2G Base
  20. Spectrolene Scarlet 2G
  21. Stabamine Scarlet GG
  22. Symulon Scarlet 2G Base


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lethal dose (50 percent kill): 400 mg/kg N/R TSCAT* OTS 206512
intraperitoneal
rat
lethal dose (50 percent kill): 400 mg/kg N/R TSCAT* OTS 206512
intravenous
mouse
lethal dose (50 percent kill): 56 mg/kg N/R CSLNX* NX#00202
oral
guinea pig
lethal dose (50 percent kill): 3,750 mg/kg Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Cyanosis
GISAAA 33(4),8,1968
oral
mouse
lethal dose (50 percent kill): 1,600 mg/kg N/R TSCAT* OTS 206512
oral
rat
lethal dose (50 percent kill): 1,600 mg/kg N/R TSCAT* OTS 206512
oral
rabbit
lethal dose (50 percent kill): 3,750 mg/kg Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Cyanosis
GISAAA 33(4),8,1968


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 27,300 mg/kg/13 week- intermittent Endocrine: Changes in spleen weight

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Catalases
GISAAA 33(4),8,1968


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4027;
Number of Industries 3;
Total Number of Facilities 116;
Number of Occupations 6;
Total Number of Employees Exposed 2,820;
Total Number of Female Employees Exposed 246


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE FEREAC 47,26992,82
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)

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