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Registry of Toxic Effects of Chemical Substances (RTECS)

Aniline, 2,4-dichloro-

RTECS #

BX2600000

CAS #

554-00-7

Updated

October 1997

Molecular Weight

162.02

Molecular Formula

C6H5Cl2N

Synonyms

2,4-Dichloranilin (German)
2,4-Dichloroaniline
2,4-Dichlorobenzenamine
Benzenamine, 2,4-dichloro- (9CI)
o,p-Dichloroaniline

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 400 mg/kgBehavioral: Muscle weakness

Lung, Thorax, or Respiration: Cyanosis

Lung, Thorax, or Respiration: Respiratory depression
TSCAT* OTS 206512
intraperitoneal/rat lethal dose (50 percent kill): 400 mg/kgBehavioral: Muscle weakness

Lung, Thorax, or Respiration: Cyanosis

Lung, Thorax, or Respiration: Respiratory depression
TSCAT* OTS 206512
oral/cat lowest published lethal dose: 113 mg/kgBehavioral: Hallucinations, distorted perceptions

Lung, Thorax, or Respiration: Cyanosis

Blood: Methemoglobinemia- Carboxhemoglobinemia
AEXPBL 72,241,1913
oral/mouse lethal dose (50 percent kill): 400 mg/kgBehavioral: Muscle weakness

Lung, Thorax, or Respiration: Cyanosis

Lung, Thorax, or Respiration: Respiratory depression
TSCAT* OTS 206512
oral/rat lethal dose (50 percent kill): 1600 mg/kgBehavioral: Muscle weakness

Lung, Thorax, or Respiration: Cyanosis

Lung, Thorax, or Respiration: Respiratory depression
TSCAT* OTS 206512

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Negative: Sperm morphology-mouse
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULEFEREAC 47,26992,82
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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