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Registry of Toxic Effects of Chemical Substances (RTECS)

Ammonium, (2,3-epoxypropyl)trimethyl-, chloride

RTECS #

BQ3480000

CAS #

3033-77-0

Updated

July 2013

Molecular Weight

151.66

Molecular Formula

C6H14NO·Cl

Synonyms

(2,3-Epoxypropyl)trimethylammonium chloride
Glycidyl-trimethyl-ammonium chloride
Glytac
Glytac A 100
G-MAC
N,N,N-Trimethyloxiranemethanaminium chloride
Oxiranemethanaminium, N,N,N-trimethyl-, chloride (9CI)
Trimethylglycidylammonium chloride

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 50 µL moderateNTIS** OTS0537063

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysisliver/rat10 mg/LMUREAV 153,57,1985
mutation in microorganisms/Klebsiella pneumoniae2 mmol/L (-enzymatic activation step)MUREAV 89,269,1981
other mutation test systems/Escherichia coli33300 µmol/LMUREAV 231,205,1990
sister chromatid exchangelung/hamster250 µmol/LMUREAV 249,55,1991
Unscheduled DNA Synthesisliver/rat20 µmol/LMUREAV 245,145,1990

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rat lethal dose (50 percent kill): 2300 µL/kgBehavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Dyspnea
NTIS** OTS0537063
skin/rabbit Lethal dose: >3160 µL/kgBehavioral: Muscle weakness

Lung, Thorax, or Respiration: Dyspnea

Skin: After systemic exposure: Dermatitis, other
NTIS** OTS0537063
subcutaneous/mouse lethal dose (50 percent kill): 90 mg/kgJCSOA9 -,176,1947

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-SWITZERLANDcarc 2, JAN2011

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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