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Registry of Toxic Effects of Chemical Substances (RTECS)

Acrylic acid, hexamethylene ester

RTECS #

AT1430000

CAS #

13048-33-4

Updated

March 2011

Molecular Weight

226.30

Molecular Formula

C12H18O4

Synonyms

1,6-Hexamethylene diacrylate
1,6-Hexanediol diacrylate
2-Propenoic acid, 1,6-hexanediyl ester
C 716
Hexaneglycol diarcylate
Kayarad HDDA
NK Ester A HD
Photomer 4017
Sartomer 238
Sartomer SR 238
Setalux UV 2243
SR 238
Viscoat 230

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /human 0.01%/24HCODEDG 5,178,1979
skin /human 0.1%/48HCODEDG 57,21,2007
skin /rabbit 500 mg/24H severeJTEHD6 19,149,1986

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/rat 7500 mg/kg (6-15D pregnant)Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)

Reproductive: Specific developmental abnormalities: Musculoskeletal system

Reproductive: Specific developmental abnormalities: Cardiovascular (circulatory) system
NTIS** OTS0571218

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lethal dose (50 percent kill): 760 mg/kgPeripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Altered sleep time (including change in righting reflex)

Behavioral: Ataxia
NTIS** OTS0571329
oral/rat lethal dose (50 percent kill): 5 gm/kgJTEHD6 19,149,1986
skin/rabbit lethal dose (50 percent kill): 3600 µL/kgJTEHD6 19,149,1986

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
skin/rabbit lowest published toxic dose: 3 gm/kg/2W- intermittentSkin: After systemic exposure: Dermatitis, otherNTIS** OTS0555406

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X3645; Number of Industries 6; Total Number of Facilities 525; Number of Occupations 8; Total Number of Employees Exposed 7874; Total Number of Female Employees Exposed 1281

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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