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Registry of Toxic Effects of Chemical Substances (RTECS)

Acrylic acid, 2,2-dimethyltrimethylene ester

RTECS #

AS8925000

CAS #

2223-82-7

Updated

September 200

Molecular Weight

212.27

Molecular Formula

C11H16O4

Synonyms

1,3-Propanediol, 2,2-dimethyl-, diacrylate
2,2-Dimethyltrimethylene acrylate
2-Propenoic acid, 2,2-dimethyl-1,3-propanediyl ester (9CI)
Acrylic acid, 2,2-dimethyl-1,3-propanediol diester
Dimethylolpropane diacrylate
Neopentyl glycol diacrylate
SR 247
Viscoat 247

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /rabbit 500 mg open irritation test severeUCDS** 11/30/1971

Tumorigenic Data and References

Route/OrganismDoseEffectReference
skin/mouse lowest published toxic dose: 46800 mg/kg/28W- intermittentTumorigenic: Carcinogenic by RTECS criteria

Skin and Appendages: Tumors

Tumorigenic: Tumors at site of application
JTEHD6 16,55,1985

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lethal dose (50 percent kill): 230 µL/kgBehavioral: Ataxia

Lung, Thorax, or Respiration: Acute pulmonary edema
NTIS** OTS0537547
oral/rat lethal dose (50 percent kill): 5190 µL/kgUCDS** 10/5/1977
skin/rabbit lethal dose (50 percent kill): 180 µL/kgLung, Thorax, or Respiration: Acute pulmonary edema

Blood: Hemorrhage

Skin: After systemic exposure: Dermatitis, other
NTIS** OTS0537547

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Hazard Survey 1974Hazard Code 83743; Number of Industries 1; Total Number of Facilities 16; Number of Occupations 5; Total Number of Employees Exposed 1264

Status in Federal Agencies

OrganizationReference
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULEFEREAC 47,26992,82
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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