Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Acetic acid, trichloro-, sodium salt

RTECS #

AJ9100000

CAS #

650-51-1

Updated

August 2003

Molecular Weight

185.36

Molecular Formula

C2Cl3O2·Na

Synonyms

ACP grass killer
Allied Arcadian Sodium TCA
Antiperz
Antyperz
Dow sodium TCA inhibited
Green cross couch grass killer
Natriumtrichlooracetaat (Dutch)
Natriumtrichloracetat (German)
Sodio(tricloroacetato di) (Italian)
Sodium (trichloracetate de) (French)
Sodium TCA
Sodium TCA inhibited
Sodium trichloroacetate
STCA
TCA sodium
Trichloressigsaures natrium (German)
Trichloroacetic acid sodium salt
Trichloroctan sodny (Czech)
Varitox
Weedmaster grass killer

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysislymphocyte/human100 mg/LTGANAK 18,318,1984
mutation in mammalian somatic cellslymphocyte/mouse2400 mg/LMUREAV 413,265,1998

Tumorigenic Data and References

Route/OrganismDoseEffectReference
oral/mouse lowest published toxic dose: 158 gm/kg/1Y- continuousTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Liver: Tumors
TXAPA9 144,235,1997

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): >365 gm/m3/4H85JFAN A377,1983
oral/cat lethal dose (50 percent kill): 4 gm/kgPeripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Somnolence (general depressed activity)

Behavioral: Muscle weakness
GISAAA 32(1),48,1967
oral/chicken lethal dose (50 percent kill): 4280 mg/kgDOEAAH 35,25,1979
oral/guinea pig lethal dose (50 percent kill): 6 gm/kgPeripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Somnolence (general depressed activity)

Behavioral: Muscle weakness
GISAAA 32(1),48,1967
oral/mouse lethal dose (50 percent kill): 3600 mg/kgPCOC** -,1061,1966
oral/rabbit lethal dose (50 percent kill): 6 gm/kgPeripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Somnolence (general depressed activity)

Behavioral: Muscle weakness
GISAAA 32(1),48,1967
oral/rat lethal dose (50 percent kill): 3320 mg/kgKSKZAN 18(3),46,1980
skin/rabbit Lethal dose: >10100 mg/kgBehavioral: Food intake (animal)NTIS** OTS0545852
skin/rat lethal dose (50 percent kill): >2 gm/kg85JFAN A377,1983
unreported route/mammal (species unspecified) lethal dose (50 percent kill): 3300 mg/kg30ZDA9 -,121,1971

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 1140 mg/kg/15D- continuousKidney, Ureter, and Bladder: Other changes in urine compositionTXCYAC 146,123,2000

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESCancelledRBREV* -,338,1998

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X8546; Number of Industries 1; Total Number of Facilities 16; Number of Occupations 1; Total Number of Employees Exposed 1462; Total Number of Female Employees Exposed 996

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
TOP