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Registry of Toxic Effects of Chemical Substances (RTECS)

Acetic acid, (3,5,6-trichloro-2-pyridyloxy)-

RTECS #

AJ9000000

CAS #

55335-06-3

Updated

February 2009

Molecular Weight

256.47

Molecular Formula

C7H4Cl3NO3

Synonyms

3,5,6-Trichloro-2-pyridyloxyacetic acid
Crossbow
Dowco 233
Garlon
Grazon ET
Redeem
Triclopyr
Turflon

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/rat 1550 mg/kg (multigenerations)Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
FAATDF 4,872,1984
oral/rat 2 gm/kg (6-15D pregnant)Reproductive: Specific developmental abnormalities: Musculoskeletal systemFAATDF 4,872,1984

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/duck lethal dose (50 percent kill): 1693 mg/kgDOEAAH 35,25,1979
oral/guinea pig lethal dose (50 percent kill): 310 mg/kgPEMNDP 9,844,1991
oral/mammal (species unspecified) lethal dose (50 percent kill): 630 mg/kgFEREAC 67,58712,2002
oral/rabbit lethal dose (50 percent kill): 550 mg/kgPEMNDP 9,844,1991
oral/rat lethal dose (50 percent kill): 630 mg/kgFMCHA2 -,C310,1991
skin/mammal (species unspecified) lethal dose (50 percent kill): >2000 mg/kgFEREAC 67,58712,2002
skin/rabbit lethal dose (50 percent kill): >2 gm/kgPEMNDP 9,844,1991

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/Dog lowest published toxic dose: 4560 mg/kg/228D- intermittentLiver: Other changes

Blood: Normocytic anemia

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
FEREAC 67,58712,2002
oral/Dog lowest published toxic dose: 4560 mg/kg/228D- intermittentLiver: Other changes

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)
FEREAC 67,58712,2002
oral/rat lowest published toxic dose: 3000 mg/kg/10D- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldREPTED 23,165,2008
oral/rat lowest published toxic dose: 300 mg/kg/10D- intermittentNutritional and Gross Metabolic: Weight loss or decreased weight gainREPTED 23,165,2008
oral/rat lowest published toxic dose: 1820 mg/kg/13W- continuousKidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)TOXID9 5,1,1985
oral/rat lowest published toxic dose: 1800 mg/kg/90D- intermittentKidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)FEREAC 67,58712,2002

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWFEREAC 72,41913,2007

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
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