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Registry of Toxic Effects of Chemical Substances (RTECS)

Acetic acid, phenyl-

RTECS #

AJ2430000

CAS #

103-82-2

Updated

November 2009

Molecular Weight

136.16

Molecular Formula

C8H8O2

Synonyms

alpha-Toluic acid
Benzenacetic acid
Benzeneacetic acid
Kyselina fenyloctova (Czech)
omega-Phenylacetic acid
Phenylacetic acid

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg/24H moderateNTIS** OTS0559218

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/rat 450 mg/kg (4D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
VPITAR 32,50,1973
oral/rat 19500 mg/kg (14D pre-4D after birth)Reproductive: Other effects on femaleHPV133 -,-,2002
oral/rat 39000 mg/kg (14D pre-4D after birth)Reproductive: Other effects on female

Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)
HPV133 -,-,2002

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 2270 mg/kgFRPSAX 13,286,1958
intraperitoneal/rat lethal dose (50 percent kill): 1600 mg/kgBCFAAI 112,53,1973
oral/guinea pig lethal dose (50 percent kill): 2250 mg/kgVPITAR 33(5),48,1974
oral/mouse lethal dose (50 percent kill): 2250 mg/kgVPITAR 33(5),48,1974
oral/rat lethal dose (50 percent kill): 2250 mg/kgVPITAR 33(5),48,1974
skin/rabbit lethal dose (50 percent kill): >5 gm/kgFCTXAV 13,901,1975
subcutaneous/mouse lethal dose (50 percent kill): 1500 mg/kgAIPTAK 116,154,1958

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X4045; Number of Industries 12; Total Number of Facilities 1636; Number of Occupations 37; Total Number of Employees Exposed 19331; Total Number of Female Employees Exposed 6627

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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