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Registry of Toxic Effects of Chemical Substances (RTECS)

Acetic acid, fluoro-

RTECS #

AH5950000

CAS #

144-49-0

Updated

April 2010

Molecular Weight

78.05

Molecular Formula

C2H3FO2

Synonyms

2-Fluoroacetic acid
Acide-monofluoracetique (French)
Acido monofluoroacetio (Italian)
Cymonic acid
Fluoroacetate
Fluoroethanoic acid
Gifblaar poison
Monofluorazijnzuur (Dutch)
Monofluoressigsaure (German)
Monofluoroacetate
Monofluoroacetic acid

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 6600 µg/kgJOCEAH 21,883,1956
intravenous/mouse lethal dose (50 percent kill): 13 mg/kgCSLNX* NX#03014
intravenous/rabbit lethal dose (50 percent kill): 250 µg/kgNATUAS 158,382,1946
oral/guinea pig lethal dose (50 percent kill): 468 µg/kgTXAPA9 13,189,1968
oral/mouse lethal dose (50 percent kill): 7 mg/kgTXAPA9 13,189,1968
oral/rat lethal dose (50 percent kill): 4680 µg/kgTXAPA9 13,189,1968
subcutaneous/mouse lethal dose (50 percent kill): 281 mg/kgJPETAB 95,62,1949
subcutaneous/rat lethal dose (50 percent kill): 5 mg/kgBehavioral: Somnolence (general depressed activity)

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Dyspnea
TXAPA9 26,93,1973
unreported route/domestic animal lowest published lethal dose: 400 µg/kgCardiac: Other changes34ZIAG -,274,1969
unreported route/rabbit lowest published lethal dose: 500 µg/kgCardiac: Other changes34ZIAG -,274,1969

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWJJATDK 26,148,2006
TOXICOLOGY REVIEWTPHSDY 29,361,2008
TOXICOLOGY REVIEWHTCWA* 2,177,

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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