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Acetic acid, fluoro -

RTECS #: AH5950000

CAS #: 144-49-0


UPDATE: November 2007 MW: 78.05 MF: C2H3FO2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STATUS IN FEDERAL AGENCIES:
  5. REFERENCES:

SYNONYMS:

  1. 2 - Fluoroacetic acid
  2. Acide - monofluoracetique (French)
  3. Acido monofluoroacetio (Italian)
  4. Cymonic acid
  5. Fluoroacetate
  6. Fluoroethanoic acid
  1. Gifblaar poison
  2. Monofluorazijnzuur (Dutch)
  3. Monofluoressigsaure (German)
  4. Monofluoroacetate
  5. Monofluoroacetic acid


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lethal dose (50 percent kill): 6,600 g/kg N/R JOCEAH 21,883,1956
intravenous
mouse
lethal dose (50 percent kill): 13 mg/kg N/R CSLNX* NX#03014
intravenous
rabbit
lethal dose (50 percent kill): 250 g/kg N/R NATUAS 158,382,1946
oral
guinea pig
lethal dose (50 percent kill): 468 g/kg N/R TXAPA9 13,189,1968
oral
mouse
lethal dose (50 percent kill): 7 mg/kg N/R TXAPA9 13,189,1968
oral
rat
lethal dose (50 percent kill): 4,680 g/kg N/R TXAPA9 13,189,1968
subcutaneous
mouse
lethal dose (50 percent kill): 281 mg/kg N/R JPETAB 95,62,1949
subcutaneous
rat
lethal dose (50 percent kill): 5 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Dyspnea
TXAPA9 26,93,1973
unreported route
domestic animal
lowest published lethal dose: 400 g/kg Cardiac: Other changes 34ZIAG -,274,1969
unreported route
rabbit
lowest published lethal dose: 500 g/kg Cardiac: Other changes 34ZIAG -,274,1969


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
JJATDK 26,148,2006


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE

34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
JOCEAH Journal of Organic Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1936-
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

RTECS Compound Description:
   Drug

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