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Registry of Toxic Effects of Chemical Substances (RTECS)

Acetic acid, cyclohexyl ester

RTECS #

AG5075000

CAS #

622-45-7

Updated

August 2009

Molecular Weight

142.22

Molecular Formula

C8H14O2

Synonyms

Cyclohexanol, acetate
Cyclohexanolazetat (German)
Cyclohexanyl acetate
Cyclohexylester kyseliny octove (Czech)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 500 mg/24H mild85JCAE -,359,1986
skin /human 100% moderateFCTOD7 46,S1,2008
skin /rabbit 100%/24H open irritation test mildFCTOD7 46,S1,2008
skin /rabbit 500 mg/24H moderateFCTXAV 17,751,1979
skin /rabbit 100 mg/24H moderate85JCAE -,359,1986

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/human lowest published toxic concentration: 3000 mg/m3/45MEye: Conjunctiva irritation

Lung, Thorax, or Respiration: Other changes
AHYGAJ 78,260,1913
oral/rat lethal dose (50 percent kill): 6730 µL/kgTXAPA9 28,313,1974
oral/rat lethal dose (50 percent kill): >5000 mg/kgFCTOD7 46,S1,2008
skin/rabbit lethal dose (50 percent kill): 10 mL/kgTXAPA9 28,313,1974
skin/rabbit lethal dose (50 percent kill): >5000 mg/kgFCTOD7 46,S1,2008
subcutaneous/cat lowest published lethal dose: 800 mg/kgAHYGAJ 78,260,1913

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWAMIHAB 21,28,1960
TOXICOLOGY REVIEWFCTOD7 46,S1,2008
TOXICOLOGY REVIEWFCTOD7 46,S52,2008
TOXICOLOGY REVIEWFCTOD7 46(12),S52,2008

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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