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Acetic acid, chloro - , methyl ester

RTECS #: AF9500000

CAS #: 96-34-4


UPDATE: February 2008 MW: 108.53 MF: C3H5ClO2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. STANDARDS AND REGULATIONS:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Chloroacetic acid methyl ester
  2. Methyl monochloracetate
  3. Methyl monochloroacetate
  1. Methylester kyseliny chloroctove (Czech)
  2. Monochloroacetic acid methyl ester


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lethal concentration (50 percent kill): 1 gm/m3/2 hour N/R 85GMAT -,82,1982
inhalation
rat
lowest published lethal concentration: 250 ppm/7 hour Kidney, Ureter, and Bladder: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TXAPA9 19,1,1971
oral
mammal (species unspecified)
lethal dose (50 percent kill): 240 mg/kg N/R GISAAA 39(4),86,1974
oral
mouse
lethal dose (50 percent kill): 240 mg/kg N/R 85GMAT -,82,1982
subcutaneous
rat
lethal dose (16 percent kill): 560 mg/kg N/R 85GMAT -,82,1982


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - DENMARK time-weighted average 1 ppm (5 mg/m3), OCT 2002
Occupational Exposure Limit - GERMANY MAK 4.5 mg/m3 (1 mL/m3) (skin, sen), 2005
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 5 mg/m3, 2003
Occupational Exposure Limit - RUSSIA short term exposure limit 5 mg/m3, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 1 ppm (5 mg/m3);
KZG- week 1 ppm (5 mg/m3), DEC2006


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4940;
Number of Industries 2;
Total Number of Facilities 22;
Number of Occupations 2;
Total Number of Employees Exposed 1,666;
Total Number of Female Employees Exposed 272


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

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