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Registry of Toxic Effects of Chemical Substances (RTECS)

Acenaphthene

RTECS #

AB1000000

CAS #

83-32-9

Updated

May 2009

Molecular Weight

154.22

Molecular Formula

C12H10

Synonyms

1,2-Dihydroacenaphthylene
1,8-Ethylenenaphthalene
Acenaphthylene, 1,2-dihydro-
Naphthyleneethylene
peri-Ethylenenaphthalene

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysislung/hamster10 mmol/L/6H (+enzymatic activation step)MUREAV 517,187,2002
mutation in microorganisms/Salmonella typhimurium0.5 nmol/plate/48H (-enzymatic activation step)MUREAV 557,99,2004
mutation in microorganisms/Salmonella typhimurium55556 pmol/L (+enzymatic activation step)MUREAV 626,88,2007
mutation in microorganisms/Other microorganisms3 mg (-enzymatic activation step)MIKBA5 54,360,1985

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lethal dose (50 percent kill): 600 mg/kgVCVGH* -,230,1990
intratracheal/rat lowest published toxic dose: 100 mg/kgKidney, Ureter, and Bladder: Other changesVCVGH* -,230,1990

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 12 mg/m3/4H/22W- intermittentLung, Thorax, or Respiration: Fibrosis, focal (pneumoconiosis)GTPZAB 14(6),46,1970
unreported route/mouse lowest published toxic dose: 180 mg/kg/12D- intermittentImmunological Including Allergic: Uncharacterized (multiple organ involvement)TOXID9 48,13,1999

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWMUREAV 540,89,2003
TOXICOLOGY REVIEWMUREAV 558,155,2004
TOXICOLOGY REVIEWMUREAV 558,7,2004
TOXICOLOGY REVIEWTOLED5 140-141,353,2003
TOXICOLOGY REVIEWMUREAV 566,209,2004
TOXICOLOGY REVIEWENTOX* -,11,2005
TOXICOLOGY REVIEWMUREAV 681,93,2009

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 10 mg/m3, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code M4337; Number of Industries 3; Total Number of Facilities 164; Number of Occupations 3; Total Number of Employees Exposed 1064
National Occupational Hazard Survey 1974Hazard Code M4337; Number of Industries 12; Total Number of Facilities 485; Number of Occupations 14; Total Number of Employees Exposed 1920

Status in Federal Agencies

OrganizationReference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/95/264370)
EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster-nondisjunction
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Polynuclear aromatic hydrocarbons by HPLC, 5506; by GC, 5515
On EPA IRIS database
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