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Registry of Toxic Effects of Chemical Substances (RTECS)

Acetamide, N,N-dimethyl-2,2-diphenyl-

RTECS #

AB8050000

CAS #

957-51-7; 73413-06-6

Updated

May 2007

Molecular Weight

239.34

Molecular Formula

C16H17NO

Synonyms

2,2-Diphenyl-N,N-dimethylacetamide
80W
Benzeneacetamide, N,N-dimethyl-alpha-phenyl- (9CI)
Dif 4
Difenamid (Czech)
Dimethylamid kyseliny difenyloctove (Czech)
Diphenamid
Diphenamide
Diphenylamide
Dymid
Enide
Enide 50
Fenam
L-34314
Lilly 34,314
N,N,Dimethyl-2,2-diphenylacetamide
N,N-Dimethyl-alpha,alpha-diphenylacetamide
N,N-Dimethyl-alpha-phenylbenzeneacetamide
N,N-Dimethyldiphenylacetamide
Rideon
U 4513
Zarur

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysisunreported route/mouse10 mg/kgTGANAK 16(1),45,1982

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 500 mg/kgGUCHAZ 6,233,1973
oral/Dog lethal dose (50 percent kill): 1 gm/kg28ZEAL 5,84,1976
oral/monkey lethal dose (50 percent kill): 1 gm/kg28ZEAL 5,84,1976
oral/mouse lethal dose (50 percent kill): 600 mg/kgPCOC** -,431,1966
oral/rabbit lethal dose (50 percent kill): 1500 mg/kg28ZEAL 5,84,1976
oral/rat lethal dose (50 percent kill): 685 mg/kgJDGRAX 12(1-2),155,1980
skin/rat lethal dose (50 percent kill): >6320 mg/kgWRPCA2 9,119,1970
subcutaneous/mouse lethal dose (50 percent kill): 800 mg/kgGUCHAZ 6,233,1973
unreported route/mammal (species unspecified) lethal dose (50 percent kill): 700 mg/kg30ZDA9 -,155,1971
unreported route/mouse lethal dose (50 percent kill): 700 mg/kgTGANAK 16(1),45,1982

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 7280 mg/kg/26W- intermittentBlood: Pigmented or nucleated red blood cells

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)
GISAAA 40(12),75,1975

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWMUTAEX 21,93,2006

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESCancelledRBREV* -,114,1998
Occupational Exposure Limit-RUSSIAshort term exposure limit 5 mg/m3, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 84343; Number of Industries 1; Total Number of Facilities 14; Number of Occupations 1; Total Number of Employees Exposed 41; Total Number of Female Employees Exposed 14
National Occupational Hazard Survey 1974Hazard Code 84343; Number of Industries 2; Total Number of Facilities 95; Number of Occupations 3; Total Number of Employees Exposed 374

Status in Federal Agencies

OrganizationReference
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database
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