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Acetamide, N,N - dimethyl - 2,2 - diphenyl -

RTECS #: AB8050000

CAS #: 957-51-7


UPDATE: May 2007 MW: 239.34 MF: C16H17NO


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. 2,2 - Diphenyl - N,N - dimethylacetamide
  2. 80W
  3. Benzeneacetamide, N,N - dimethyl - alpha - phenyl - (9CI)
  4. Dif 4
  5. Difenamid (Czech)
  6. Dimethylamid kyseliny difenyloctove (Czech)
  7. Diphenamid
  8. Diphenamide
  9. Diphenylamide
  10. Dymid
  11. Enide
  1. Enide 50
  2. Fenam
  3. L - 34314
  4. Lilly 34,314
  5. N,N,Dimethyl - 2,2 - diphenylacetamide
  6. N,N - Dimethyldiphenylacetamide
  7. N,N - Dimethyl - alpha,alpha - diphenylacetamide
  8. N,N - Dimethyl - alpha - phenylbenzeneacetamide
  9. Rideon
  10. U 4513
  11. Zarur


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis unreported route
mouse
10 mg/kg TGANAK 16(1),45,1982


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lethal dose (50 percent kill): 500 mg/kg N/R GUCHAZ 6,233,1973
oral
dog
lethal dose (50 percent kill): 1 gm/kg N/R 28ZEAL 5,84,1976
oral
monkey
lethal dose (50 percent kill): 1 gm/kg N/R 28ZEAL 5,84,1976
oral
mouse
lethal dose (50 percent kill): 600 mg/kg N/R PCOC** -,431,1966
oral
rat
lethal dose (50 percent kill): 685 mg/kg N/R JDGRAX 12(1-2),155,1980
oral
rabbit
lethal dose (50 percent kill): 1,500 mg/kg N/R 28ZEAL 5,84,1976
subcutaneous
mouse
lethal dose (50 percent kill): 800 mg/kg N/R GUCHAZ 6,233,1973
skin
rat
lethal dose (50 percent kill): >6,320 mg/kg N/R WRPCA2 9,119,1970
unreported route
mammal (species unspecified)
lethal dose (50 percent kill): 700 mg/kg N/R 30ZDA9 -,155,1971
unreported route
mouse
lethal dose (50 percent kill): 700 mg/kg N/R TGANAK 16(1),45,1982


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 7,280 mg/kg/26 week- intermittent Blood: Pigmented or nucleated red blood cells

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)
GISAAA 40(12),75,1975


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
MUTAEX 21,93,2006


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,114,1998
Occupational Exposure Limit - RUSSIA short term exposure limit 5 mg/m3, JUN2003


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84343;
Number of Industries 2;
Total Number of Facilities 95;
Number of Occupations 3;
Total Number of Employees Exposed 374
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84343;
Number of Industries 1;
Total Number of Facilities 14;
Number of Occupations 1;
Total Number of Employees Exposed 41;
Total Number of Female Employees Exposed 14


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada)
JDGRAX Journal of Drug Research. (National Organization for Drug Research and Control, POB 29, Cairo, Egypt) V.2- 1969-
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-
PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS)
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967-
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued.

Used as a selective preemergence herbicide

RTECS Compound Description:
   Agricultural Chemical
   Mutagen

ALT CAS #: 73413-06-6
Click Here for Additional Information about RTECS

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