CDC logo, Safer Healthier People  CDC HomeCDC SearchCDC Health Topics A-Z
NIOSH - National Institute for Occupational Safety and Health

Search NIOSH  |  NIOSH Home  |  NIOSH Topics  |  Site Index  |  Databases and Information Resources  |  NIOSH Products  |  Contact Us






o - Toluidine

RTECS #: XU2975000

CAS #: 95-53-4


UPDATE: May 2009 MW: 107.17 MF: C7H9N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REPRODUCTIVE EFFECTS DATA:
  5. TUMORIGENIC DATA:
  6. ACUTE TOXICITY DATA:
  7. OTHER MULTIPLE DOSE DATA:
  8. REVIEWS:
  9. STANDARDS AND REGULATIONS:
  10. NIOSH DOCUMENTATION AND SURVEILLANCE:
  11. STATUS IN FEDERAL AGENCIES:
  12. REFERENCES:

SYNONYMS:

  1. 1 - Amino - 2 - methylbenzene
  2. 1 - Methyl - 2 - aminobenzene
  3. 2 - Amino - 1 - methylbenzene
  4. 2 - Aminotoluene
  5. 2 - Methyl - 1 - aminobenzene
  6. 2 - Methylaniline
  7. 2 - Methylbenzenamine
  8. 2 - Toluidine
  9. Aniline, 2 - methyl -
  10. Benzenamine, 2 - methyl - (9CI)
  1. C.I. 37077
  2. RCRA waste number U328
  3. o - Aminotoluene
  4. o - Methylaniline
  5. o - Methylbenzenamine
  6. o - Toluidin (Czech)
  7. o - Toluidine (ACGIH:OSHA)
  8. o - Toluidyna (Polish)
  9. o - Tolylamine
  10. ortho - Toluidine


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
750 g/24 hour severe 85JCAE -,460,1986
skin
rabbit
10 mg/24 hour open irritation test mild AIHAAP 23,95,1962
skin
rabbit
500 mg/24 hour mild 85JCAE -,460,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
body fluid assay rat
Salmonella typhimurium
300 mg/kg MUREAV 79,173,1980
body fluid assay rat
ovary
400 mg/kg MUREAV 143,263,1985
cytogenetic analysis hamster liver 12 mg/L PMRSDJ 5,397,1985
cytogenetic analysis hamster lung 1 gm/L PMRSDJ 5,427,1985
cytogenetic analysis hamster ovary 250 mg/L PMRSDJ 5,413,1985
cytogenetic analysis rat liver 175 mg/L PMRSDJ 5,387,1985
DNA damage hamster ovary 20 mmol/L PMRSDJ 5,367,1985
DNA damage human other cell types 16 mmol/L/20 hour TXCYAC 179,115,2002
DNA damage intraperitoneal
mouse
100 mg/kg ATSUDG 5,355,1982
DNA damage oral
mouse
600 mg/kg MUREAV 440,1,1999
DNA damage rat liver 319 mg/L PMRSDJ 5,353,1985
DNA damage rat other cell types 8 mmol/L/20 hour TXCYAC 179,115,2002
DNA inhibition human HeLa cell 4 mmol/L CRNGDP 13,2389,1992
DNA inhibition intraperitoneal
mouse
20 gm/kg ARGEAR 51,605,1981
DNA inhibition oral
mouse
200 mg/kg MUREAV 46,305,1977
DNA repair Escherichia coli 20 L/plate JJIND8 62,873,1979
unscheduled DNA synthesis human HeLa cell 50 L/L PMRSDJ 5,347,1985
unscheduled DNA synthesis rat liver 1 mmol/L PMRSDJ 5,371,1985
mutation in microorganisms human lymphocyte 300 mg/L (+enzymatic activation step) PMRSDJ 5,497,1985
mutation in microorganisms mouse lymphocyte 12,500 g/L (+enzymatic activation step) PMRSDJ 5,525,1985
mutation in microorganisms mouse embryo 250 mg/L (+enzymatic activation step) PMRSDJ 5,639,1985
mutation in microorganisms Salmonella typhimurium 40 g/plate (-enzymatic activation step) PJABDW 53,34,1977
mutation in microorganisms Salmonella typhimurium 250 ng/plate (+enzymatic activation step) AGSREJ 13,13,1995
mutation in microorganisms Saccharomyes cerevisiae 378 mg/L (+/-enzymatic activation step) PMRSDJ 5,271,1985
micronucleus test human lymphocyte 2 mmol/L MUREAV 291,93,1993
micronucleus test multiple
non-mammalian species
4 ppm MUREAV 292,83,1993
micronucleus test intraperitoneal
rat
300 mg/kg MUREAV 583,133,2005
micronucleus test oral
rat
600 mg/kg MUREAV 583,133,2005
gene conversion and mitotic recombination Saccharomyes cerevisiae 378 mg/L PMRSDJ 5,271,1985
mutation in mammalian somatic cells human lymphocyte 450 mg/L PMRSDJ 5,497,1985
mutation in mammalian somatic cells mouse lymphocyte 10 mg/L PMRSDJ 5,587,1985
morphological transform hamster embryo 100 mg/L PMRSDJ 5,665,1985
morphological transform mouse embryo 500 mg/L PMRSDJ 5,659,1985
phage inhibition capacity Escherichia coli 100 mmol/L MDMIAZ 31,11,1979
sister chromatid exchange intraperitoneal
hamster
200 mg/kg MUREAV 113,33,1983
sister chromatid exchange oral
hamster
200 mg/kg MUREAV 113,33,1983
sister chromatid exchange hamster ovary 125 mg/L PMRSDJ 5,451,1985
sister chromatid exchange hamster lung 2,500 mol/L PMRSDJ 5,469,1985
sister chromatid exchange human lymphocyte 200 mol/L MUREAV 211,77,1989
sister chromatid exchange rat liver 21,800 g/L PMRSDJ 5,387,1985
sex chromosome loss and nondisjunction hamster liver 60 mg/L PMRSDJ 5,397,1985
specific locus test oral
Drosophila melanogaster
1 mmol/L PMRSDJ 5,313,1985


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
skin
rat
lowest published toxic dose: 9,520 mg/kg (17 week male) Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Reproductive: Effects on newborn: Physical
GTPZAB 27(9),47,1983
skin
rat
lowest published toxic dose: 9,520 mg/kg (17 week prior to copulation) Reproductive: Maternal effects: Menstrual cycle changes or disorders

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Effects on newborn: Physical
GTPZAB 27(9),47,1983
skin
rat
lowest published toxic dose: 952 mg/kg (17 week prior to copulation) Reproductive: Maternal effects: Ovaries, fallopian tubes

Reproductive: Maternal effects: Menstrual cycle changes or disorders
GTPZAB 27(9),47,1983


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 109 gm/kg/2 year- continuous Tumorigenic: Neoplastic by RTECS criteria

Blood: Tumors
FCTOD7 25,619,1987
oral
rat
toxic dose : 7,250 mg/kg/23 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Kidney, Ureter, and Bladder: Bladder tumors
APMIAL 26,447,1949
subcutaneous
mouse
lowest published toxic dose: 320 mg/kg (15-21 day pregnant) Tumorigenic: Neoplastic by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Reproductive: Tumorigenic effects: Transplacental tumorigenesis
BEXBAN 78,1402,1974
subcutaneous
rabbit
lowest published toxic dose: 840 mg/kg/14 week- intermittent Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Kidney, Ureter, and Bladder: Bladder tumors
IMEMDT 27,155,1982


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
man
lowest published toxic concentration: 25 mg/m3 Kidney, Ureter, and Bladder: Urine volume increased

Kidney, Ureter, and Bladder: Hematuria

Blood: Methemoglobinemia- Carboxhemoglobinemia
GTPZAB 14(8),7,1970
inhalation
rat
lethal concentration (50 percent kill): 862 ppm/4 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Tremor

Lung, Thorax, or Respiration: Cyanosis
NTIS** OTS0570956
intraperitoneal
mouse
lethal dose (50 percent kill): 150 mg/kg N/R NTIS** AD691-490
oral
cat
lowest published lethal dose: 150 mg/kg Behavioral: Coma

Lung, Thorax, or Respiration: Dyspnea

Blood: Methemoglobinemia- Carboxhemoglobinemia
XPHBAO 271,49,1941
oral
frog
lowest published lethal dose: 151 mg/kg Behavioral: Coma

Lung, Thorax, or Respiration: Dyspnea

Blood: Methemoglobinemia- Carboxhemoglobinemia
XPHBAO 271,49,1941
oral
mammal (species unspecified)
lethal dose (50 percent kill): 1,700 mg/kg N/R GTPZAB 32(10),25,1988
oral
mouse
lethal dose (50 percent kill): 520 mg/kg Blood: Normocytic anemia

Blood: Pigmented or nucleated red blood cells

Blood: Methemoglobinemia- Carboxhemoglobinemia
IMEMDT 27,155,1982
oral
mouse
lethal dose (50 percent kill): 520 mg/kg N/R ENTOX* -,206,2005
oral
rat
lethal dose (50 percent kill): 670 mg/kg Blood: Normocytic anemia

Blood: Pigmented or nucleated red blood cells

Blood: Methemoglobinemia- Carboxhemoglobinemia
IMEMDT 27,155,1982
oral
rat
lowest published toxic dose: 60 mg/kg Liver: Other changes

Kidney, Ureter, and Bladder: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
TXCYAC 186,67,2003
oral
rat
lethal dose (50 percent kill): 670 mg/kg N/R ENTOX* -,206,2005
oral
rabbit
lethal dose (50 percent kill): 840 mg/kg Blood: Normocytic anemia

Blood: Pigmented or nucleated red blood cells

Blood: Methemoglobinemia- Carboxhemoglobinemia
IMEMDT 27,155,1982
skin
rabbit
lethal dose (50 percent kill): 3,250 L/kg N/R AIHAAP 23,95,1962


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 1,125 mg/kg/5 day- continuous Blood: Changes in spleen

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
FAATDF 3,285,1983
oral
rat
lowest published toxic dose: 10,200 mg/kg/30 day- intermittent Kidney, Ureter, and Bladder: Proteinuria

Blood: Normocytic anemia

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VINIT* #4035-77
oral
rat
lowest published toxic dose: 1,125 mg/kg/5 day- intermittent Blood: Methemoglobinemia- Carboxhemoglobinemia

Blood: Changes in spleen
CICAD* VI:7,1,1998
oral
rat
lowest published toxic dose: 1,148 mg/kg/4 week- continuous Liver: Other changes

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
IJTOFN 24,365,2005
oral
rat
lowest published toxic dose: 2,086 mg/kg/2 week- continuous Nutritional and Gross Metabolic: Weight loss or decreased weight gain IJTOFN 24,365,2005
oral
rat
lowest published toxic dose: 2,190 mg/kg/30 day- continuous Blood: Methemoglobinemia- Carboxhemoglobinemia IJTOFN 24,365,2005
oral
rat
lowest published toxic dose: 4,004 mg/kg/91 day- continuous Blood: Methemoglobinemia- Carboxhemoglobinemia IJTOFN 24,365,2005


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 2 ppm (skin) DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed animal carcinogen DTLVS* TLV/BEI,2007
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 77,564,2000
International Agency for Research on Cancer (IARC) Cancer Review Human Limited Evidence IMEMDT 77,564,2000
International Agency for Research on Cancer (IARC) Cancer Review Group 2A IMEMDT 77,564,2000
TOXICOLOGY REVIEW
MUREAV 543,201,2003
TOXICOLOGY REVIEW
MUREAV 567,109,2004
TOXICOLOGY REVIEW
TCMUD8 23(Suppl 1),187,2003
TOXICOLOGY REVIEW
TXCYAC 196,1,2004
TOXICOLOGY REVIEW
MUREAV 588,88,2005
TOXICOLOGY REVIEW
FCTOD7 44,1699,2006
TOXICOLOGY REVIEW
MUREAV 627,10,2007
TOXICOLOGY REVIEW
ENTOX* -,104,2005
TOXICOLOGY REVIEW
MUREAV 627,59,2007
TOXICOLOGY REVIEW
ENTOX* -,206,2005
TOXICOLOGY REVIEW
ENTOX* -,206,2005
TOXICOLOGY REVIEW
BCLPT* 96,131,2005
TOXICOLOGY REVIEW
MUREAV 584,1,2005
TOXICOLOGY REVIEW
MUREAV 654,114,2008
TOXICOLOGY REVIEW
MUREAV 654,114,2008


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 5 ppm (22 mg/m3) DTLVS* 3,261,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 5 ppm (22 mg/m3) (skin) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 5 ppm (22 mg/m3) (skin) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 5 ppm (22 mg/m3) (skin) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 5 ppm (22 mg/m3) (skin) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 2 ppm (8.8 mg/m3), Carcinogen, JUL2008
Occupational Exposure Limit - AUSTRIA TRK 0.5 mg/m3, JAN 2006
Occupational Exposure Limit - BELGIUM time-weighted average 2 ppm (8.9 mg/m3), Skin, Carcinogen, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 2 ppm (9 mg/m3), OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 5 ppm (22 mg/m3), short term exposure limit 10 ppm (44 mg/m3), Skin, Carcinogen, JAN1999
Occupational Exposure Limit - FRANCE VME 2 ppm (9 mg/m3), continuous2 Carcinogen, FEB2006
Occupational Exposure Limit - HUNGARY ceiling concentration 0.5 mg/m3, Skin, Carcinogen, SEP2000
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 1 ppm (4.4 mg/m3), skin, 2B carcinogen, APR2007
Occupational Exposure Limit - KOREA time-weighted average 2 ppm (9 mg/m3), carcinogen, skin, 2006
Occupational Exposure Limit - MEXICO time-weighted average 5 ppm (22 mg/m3) (skin), 2004
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.2 ppm (0.89 mg/m3), skin, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 1 ppm (4.5 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 5 ppm (22 mg/m3), Skin, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 3 mg/m3, MAC(short term exposure limit) 9 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 0.5 mg/m3, short term exposure limit 1 mg/m3, Skin, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 0.1 ppm (0.5 mg/m3), Skin, Carcinogen, DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 5 ppm (22 mg/m3), Skin, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.2 ppm (0.89 mg/m3) (skin), 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Confirmed animal carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Confirmed animal carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO o-TOLUIDINE-air Carcinogen lowest feasible concentration (Sk) NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 73470;
Number of Industries 21;
Total Number of Facilities 2,912;
Number of Occupations 20;
Total Number of Employees Exposed 13,053
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 73470;
Number of Industries 32;
Total Number of Facilities 2,517;
Number of Occupations 25;
Total Number of Employees Exposed 30,019;
Total Number of Female Employees Exposed 15,501


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
EPA GENETOX PROGRAM 1988, Positive: Cell transform.-RLV F344 rat embryo
EPA GENETOX PROGRAM 1988, Positive: E coli polA without S9
EPA GENETOX PROGRAM 1988, Negative: Sperm morphology-mouse; S cerevisiae-homozygosis
EPA GENETOX PROGRAM 1988, Inconclusive: Histidine reversion-Ames test
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an intermediate in the manufacture of dyes and in production of o-AMINOAZOTOLUENE
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Amines, aromatic, 2002
NTP 11th Report on Carcinogens,2004:Reasonably anticipated to be a human carcinogen
OSHA ANALYTICAL METHOD #ID-73


REFERENCES:

CODEN
REFERENCE

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AGSREJ Arab Gulf Journal of Scientific Research. (Arab Bureau of Education for the Gulf States, POB 3908, Riyadh, 11481, Saudi Arabia) V.7 No.2- 1989-
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
APMIAL Acta Pathologica et Microbiologica Scandinavica. (Copenhagen, Denmark) V.1-77, 1924-69. For publisher information, see ACPADQ.
ARGEAR Archiv fuer Geschwulstforschung. (VEB Verlag Volk und Gesundheit Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1949-
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978-
BCLPT* Basic & clinical pharmacology & toxicology (Copenhagen, Denmark : Nordic Pharmacological Society Oxford, UK : Distributed by Blackwell Munksgaard) V.94- 2004-
BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CICAD* TA:Concise International Chemical Assessment Document (CICAD)
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
IJTOFN International Journal of Toxicology. (Taylor & Francis, 47 Runway Rd., Suite g, Levittown, PA 19057) V.16- 1997-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ.
MDMIAZ Medycyna Doswiadczalna i Mikrobiologia. For English translation, see EXMMAV. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1949-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
PJABDW Proceedings of the Japan Academy, Series B: Physical and Biological Sciences. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.53- 1977-
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981-
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-
VINIT* Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii (VINITI). All-Union Institute of Scientific and Technical Information. (Moscow, USSR) Use information broker to obtain publications.
XPHBAO U.S. Public Health Service, Public Health Bulletin. (Washington, DC)

Used as an intermediate in the manufacture of dyes and in production of o-AMINOAZOTOLUENE

NIOSH PROFILE (AMINES, PRIMARY AROMATIC), SRI, 2/77

RTECS Compound Description:
   Tumorigen
   Mutagen
   Reproductive Effector
   Human Data
   Primary Irritant

Click Here for Additional Information about RTECS

NIOSH Home |  NIOSH Search  |  Site Index  |  Topic List |  Contact Us