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Methane, dibromodifluoro -

RTECS #: PA7525000

CAS #: 75-61-6


UPDATE: May 2009 MW: 209.83 MF: CBr2F2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Difluorodibromomethane
  2. Difluorodibromomethane (ACGIH:OSHA)
  1. Freon 12 - B2
  2. Halon 1202


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lethal concentration (50 percent kill): 140 gm/m3/2 hour Behavioral: Rigidity (includes catalepsy)

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes
TLSMA6 111,10,1975
inhalation
mouse
lethal concentration (50 percent kill): 259,200 mg/m3/2 hour N/R VCVGH* -,623,1990
inhalation
rat
lethal concentration (50 percent kill): 210,600 mg/m3/4 hour N/R VCVGH* -,623,1990
inhalation
rat
lowest published lethal concentration: 470,000 mg/m3/15 minute N/R VCVGH* -,623,1990


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 100 ppm DTLVS* TLV/BEI,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 100 ppm (860 mg/m3) DTLVS* 3,86,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 100 ppm (860 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 100 ppm (860 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 100 ppm (860 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 100 ppm (860 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 100 ppm (858 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 100 ppm (870 mg/m3), MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 100 ppm (860 mg/m3), OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 100 ppm (860 mg/m3), short term exposure limit 150 ppm (1290 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 100 ppm (860 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 870 mg/m3 (100 mL/m3), 2005
Occupational Exposure Limit - KOREA time-weighted average 100 ppm (860 mg/m3), 2006
Occupational Exposure Limit - MEXICO time-weighted average 100 ppm (860 mg/m3);
short term exposure limit 150 ppm (1290 mg/m3), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 860 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 100 ppm (858 mg/m3), JAN2002
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 100 ppm (860 mg/m3), JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 100 ppm (860 mg/m3),KZG- week 200 ppm (1720 mg/m3), DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 100 ppm (860 mg/m3), JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 100 ppm
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 100 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DIFLUORODIBROMOMETHANE-air 10 hour time-weighted average 100 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 25515;
Number of Industries 2;
Total Number of Facilities 40;
Number of Occupations 3;
Total Number of Employees Exposed 2,234
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 25515;
Number of Industries 1;
Total Number of Facilities 7;
Number of Occupations 1;
Total Number of Employees Exposed 28


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Difluorodibromomethane, 1012


REFERENCES:

CODEN
REFERENCE

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. (Leningrad, Russia) V.1-145, 1949-82. Discontinued.
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

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