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Hydrogen peroxide, 90%

RTECS #: MX0900000

CAS #: 7722-84-1


UPDATE: May 2009 MW: 34.02 MF: H2O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. TUMORIGENIC DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. REVIEWS:
  8. STANDARDS AND REGULATIONS:
  9. NIOSH DOCUMENTATION AND SURVEILLANCE:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. Albone
  2. Dihydrogen dioxide
  3. Hioxyl
  4. Hydrogen dioxide
  5. Hydrogen peroxide
  6. Hydrogen peroxide (ACGIH:OSHA)
  7. Hydroperoxide
  8. Inhibine
  9. Oxydol
  10. Perhydrol
  1. Perone
  2. Perossido di idrogeno (Italian)
  3. Peroxan
  4. Peroxide
  5. Peroxyde d'hydrogene (French)
  6. Superoxol
  7. T - Stuff
  8. Wasserstoffperoxid (German)
  9. Waterstofperoxyde (Dutch)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
1 mg severe JTPAE7 29,308,2001


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis hamster ovary 1 mmol/L CALEDQ 5,199,1978
cytogenetic analysis hamster lung 100 Ámol/L IDZAAW 56,1,1981
cytogenetic analysis hamster embryo 100 Ámol/L IDZAAW 56,1,1981
cytogenetic analysis hamster fibroblast 250 mg/L ESKHA5 (96),55,1978
cytogenetic analysis hamster ovary 0.3 mmol/L/1 hour MUREAV 649,114,2008
cytogenetic analysis human other cell types 1.5 mg/L/4 hour MUREAV 578,100,2005
cytogenetic analysis human lymphocyte 30 Ámol/L/30 minute MUREAV 559,97,2004
cytogenetic analysis mouse Ascites tumor 10 mmol/L MUREAV 4,385,1967
cytogenetic analysis mouse embryo 10 Ámol/L IDZAAW 56,1,1981
DNA adduct hamster embryo 0.9 Ámol/L/1 hour MUREAV 563,35,2004
DNA adduct human lymphocyte 25 Ámol/L/1 hour MUREAV 582,155,2005
DNA damage Bacillus subtilis 50 mmol/L BBACAQ 155,476,1968
DNA damage cattle other cell types 25 Ámol/L MUREAV 240,35,1990
DNA damage Escherichia coli 0.1 Ámol/plate/2 hour MUREAV 535,171,2003
DNA damage hamster ovary 20 Ámol/L MUREAV 299,95,1993
DNA damage hamster lung 353 Ámol/L NATUAS 282,318,1979
DNA damage hamster lung 200 Ámol/L/24 hour ARTODN 75,604,2001
DNA damage hamster ovary 200 Ámol/L/5 minute MUREAV 560,41,2004
DNA damage hamster lung 150 Ámol/L/1 hour MUREAV 631,44,2007
DNA damage hamster other cell types 40 Ámol/L/1 hour MUREAV 559,39,2004
DNA damage hamster ovary 0.9 mmol/L/1 hour MUREAV 649,114,2008
DNA damage human fibroblast 28 Ámol/L BBACAQ 781,56,1984
DNA damage human lymphocyte 100 Ámol/L JCINAO 77,1312,1986
DNA damage human leukocyte 20 Ámol/L MUREAV 265,255,1992
DNA damage human lung 300 Ámol/L/1 hour MUREAV 515,99,2002
DNA damage human other cell types 100 Ámol/L/3 hour MUTAEX 16,439,2001
DNA damage human other cell types 10 Ámol/L/15 minute MUREAV 519,151,2002
DNA damage human lymphocyte 0.1 mmol/L/5 minute MUREAV 508,157,2002
DNA damage human lymphocyte 0.1 mmol/L/1 hour MUREAV 535,25,2003
DNA damage human other cell types 0.1 mmol/L/1 hour MUREAV 535,25,2003
DNA damage human other cell types 0.375 mmol/L/5 minute MUREAV 526,19,2003
DNA damage human lymphocyte 0.1 mmol/L/30 minute TCMUD8 20,11,2000
DNA damage human sperm 80 Ámol/L/1 hour MUREAV 544,173,2003
DNA damage human lymphocyte 1 Ámol/L/2 hour TOSCF2 72,283,2003
DNA damage human fibroblast 50 mmol/L/1 hour TOLED5 147,35,2004
DNA damage human lymphocyte 100 Ámol/L/3 minute MUREAV 587,52,2005
DNA damage human other cell types 100 Ámol/L/3 minute MUREAV 587,52,2005
DNA damage human mammary gland 9.8 mg/L/24 hour (-enzymatic activation step) MUREAV 588,47,2005
DNA damage human other cell types 18.75 Ámol/L TOXID9 66,307,2002
DNA damage human other cell types 200 Ámol/L/60 minute MUREAV 577S,1,2005
DNA damage human other cell types 2,000 Ámol/L/3 hour (-enzymatic activation step) MUTAEX 20,193,2005
DNA damage human lymphocyte 5.0 mg/L/48 hour MUREAV 607,160,2006
DNA damage human fibroblast 100 Ámol/L/20 minute MUREAV 546,93,2004
DNA damage human other cell types 25 Ámol/L/30 minute TOLED5 170,57,2007
DNA damage human other cell types 50 Ámol/L/10 minute FCTOD7 46,1221,2008
DNA damage human liver 56 Ámol/L/10 minute MUREAV 657,133,2008
DNA damage mammal (species unspecified) lymphocyte 600 Ámol/L DECRDP 8,1,1982
DNA damage mouse other cell types 100 Ámol/L JCINAO 77,1312,1986
DNA damage mouse other cell types 1 Ámol/L CRNGDP 4,1507,1983
DNA damage mouse lymphocyte 2 mmol/L MUREAV 203,155,1988
DNA damage mouse other cell types 0.1 mmol/L/1 hour MUREAV 535,25,2003
DNA damage mouse other cell types 200 Ámol/L/1 hour (-enzymatic activation step) MUREAV 541,9,2003
DNA damage mouse fibroblast 25 Ámol/L/15 minute MUREAV 531,165,2003
DNA damage mouse liver 50 Ámol/L/1 hour TOXID9 44,153,2005
DNA damage mouse fibroblast 500 Ámol/L /1 hour FCTOD7 44,261,2006
DNA damage mouse other cell types 50 Ámol/L MUTAEX 20,469,2005
DNA damage non-mammalian species other cell types 0.4 mmol/L/1 hour MUREAV 539,19,2003
DNA damage non-mammalian species other cell types 44 Ámol/L/20 minute MUREAV 542,15,2003
DNA damage Neurospora crassa 50 Ámol/L MUREAV 405,29,1998
DNA damage other fish other cell types 0.1 mmol/L/5 minute MUREAV 534,165,2003
DNA damage other microorganisms 1 mmol/L MUREAV 368,235,1996
DNA damage rat other cell types 200 Ámol/L CRNGDP 20,629,1999
DNA damage rat liver 300 Ámol/L/1 hour MUREAV 515,99,2002
DNA damage rat other cell types 10 Ámol/L/24 hour ATSUDG 75,243,2001
DNA damage rat other cell types 75 Ámol/L/5 minute TOLED5 159,212,2005
DNA damage rat lymphocyte 50 Ámol/L/5 minute TOLED5 164,54,2006
DNA damage rat testis 50 Ámol/L/5 minute TOLED5 164,54,2006
DNA damage rat lung 50 Ámol/L/5 minute TOLED5 164,54,2006
DNA damage rat liver 50 Ámol/L/5 minute TOLED5 164,54,2006
DNA damage rat other cell types 100 Ámol/L/10 minute MUREAV 634,51,2007
DNA damage rat other cell types 1 mmol/L/30 minute NRTXDN 28,886,2007
DNA damage rat other cell types 0.1 mmol/L/6 hour NRTXDN 28,886,2007
DNA damage rat lymphocyte 50 Ámol/L/10 minute MUREAV 564,75,2004
DNA damage salmon embryo 5 Ámol/L/1 hour MUREAV 563,89,2004
DNA damage woman other cell types 1 mmol/L/1 hour TXCYAC 222,71,2006
DNA inhibition human other cell types 1,200 Ámol/L CNREA8 45,2522,1985
DNA inhibition human fibroblast 1 mg/L CRNGDP 4,1317,1983
DNA inhibition mouse other cell types 40 Ámol/L JCINAO 77,1312,1986
DNA repair Escherichia coli 14,630 Ág/well/16 hour CBINA8 15,219,1976
DNA repair human fibroblast 20 Ámol/L/1 hour MUREAV 513,159,2002
DNA repair human other cell types 10 mmol/L/10 minute MUREAV 537,1,2003
DNA repair human other cell types 10 Ámol/L/20 minute MUREAV 577S,1,2005
DNA repair Salmonella typhimurium 2 mmol/L/60 minute MUREAV 502,11,2002
unscheduled DNA synthesis human fibroblast 1 mmol/L CALEDQ 5,199,1978
unscheduled DNA synthesis human lung 600 Ág/L ENMUDM 5,177,1983
mutation in microorganisms Bacillus subtilis 5 ppm (-enzymatic activation step) MUREAV 95,191,1982
mutation in microorganisms Bacillus subtilis 5 pph/15 minute MUREAV 503,77,2002
mutation in microorganisms Escherichia coli 5 pph (-enzymatic activation step) AGACBH 4,286,1974
mutation in microorganisms Escherichia coli 100 Ág/plate/48 hour (+/-enzymatic activation step) MUREAV 539,29,2003
mutation in microorganisms Haemophilus influenzae 800 Ámol/L (-enzymatic activation step) MUREAV 30,9,1975
mutation in microorganisms Neurospora crassa 210 mmol/L/30 minute (-enzymatic activation step) PNASA6 35,581,1949
mutation in microorganisms other microorganisms 6 ppm/1 hour- continuous (-enzymatic activation step) JOBAAY 54,767,1947
mutation in microorganisms other microorganisms 6 ppm (-enzymatic activation step) POASAD 34,114,1953
mutation in microorganisms Salmonella typhimurium 6 Ág/plate (-enzymatic activation step) ABCHA6 44,1989,1980
mutation in microorganisms Salmonella typhimurium 1.87 mg/plate/30 minute MUREAV 535,171,2003
mutation in microorganisms Salmonella typhimurium 25 Ág/plate/48 hour (+/-enzymatic activation step) MUREAV 539,29,2003
mutation in microorganisms Salmonella typhimurium 500 Ág/plate/66 hour (-enzymatic activation step) EMMUEG 40,63,2002
mutation in microorganisms Salmonella typhimurium 34,000 ng/plate/72 hour MUREAV 542,49,2003
mutation in microorganisms Salmonella typhimurium 51 Ág/plate/72 hour (-enzymatic activation step) MUTAEX 15,495,2000
mutation in microorganisms Salmonella typhimurium 20 ÁL/plate/30 minute DCTODJ 27,157,2004
mutation in microorganisms Salmonella typhimurium 2.6 mmol/L/2 hour MUREAV 578,225,2005
mutation in microorganisms Salmonella typhimurium 3 mg/L/2 hour (-enzymatic activation step) MUREAV 578,210,2005
mutation in microorganisms Saccharomyes cerevisiae 10 mg/L (-enzymatic activation step) MUREAV 33,147,1975
mutation in microorganisms Saccharomyes cerevisiae 68.5 mg/L/16 hour MUTAEX 20,105,2004
mutation in microorganisms Saccharomyes cerevisiae 2 Ámol/l MUREAV 547,123,2004
mutation in microorganisms Schizosaccharomyces pombe 2,820 mmol/L (-enzymatic activation step) ADWMAX -,193,1962
micronucleus test hamster embryo 5 mg/L/4 hour (-enzymatic activation step) MUREAV 561,153,2004
micronucleus test hamster ovary 500 Ámol/L/24 hour (-enzymatic activation step) MUREAV 630,1,2007
micronucleus test hamster lung 150 Ámol/L/1 hour MUREAV 631,44,2007
micronucleus test human lymphocyte 3.4 mg/L/24 hour EMMUEG 43,45,2004
micronucleus test human other cell types 10 Ámol/L MUREAV 577S,1,2005
micronucleus test human lymphocyte 30 Ámol/L/30 minute MUREAV 559,97,2004
gene conversion and mitotic recombination Saccharomyes cerevisiae 5 pph AGACBH 4,286,1974
mutation in mammalian somatic cells hamster lung 10 Ámol/L CRNGDP 10,1055,1989
mutation in mammalian somatic cells monkey kidney 7 mmol/L CRNGDP 11,283,1990
mutation in mammalian somatic cells mouse lymphocyte 18,600 nmol/L MUTAEX 3,193,1988
morphological transform hamster embryo 2,500 Ág/L MUREAV 356,85,1996
morphological transform mouse embryo 20 Ámol/L CRNGDP 10,1055,1989
morphological transform rat liver 100 Ámol/L/7 week MOCAE8 30,209,2001
other mutation test systems Bacillus subtilis 100 Ámol/L MUREAV 4,517,1967
other mutation test systems Escherichia coli 100 Ámol/L MUREAV 203,81,1988
other mutation test systems human other cell types 1,200 Ámol/L CNREA8 45,2522,1985
other mutation test systems human other cell types 0.5 mmol/L/6 hour MUREAV 648,15,2008
other mutation test systems Salmonella typhimurium 45 mg/L MUREAV 192,239,1987
phage inhibition capacity Escherichia coli 500 ng/well MUREAV 260,349,1991
sister chromatid exchange hamster lung 40 Ámol/L MUREAV 174,21,1986
sister chromatid exchange hamster ovary 80 Ámol/L MUREAV 224,269,1989
sister chromatid exchange hamster ovary 0.75 mmol/L/1 hour MUREAV 649,114,2008
sister chromatid exchange Saccharomyes cerevisiae 0.4 pph MUREAV 547,123,2004
specific locus test Escherichia coli 2.5 mmol/L/10 minute MUREAV 508,107,2002
specific locus test Escherichia coli 1 Ámol/L/4 hour MUREAV 560,27,2004
specific locus test Escherichia coli 50 Ámol/L/30 minute MUREAV 628,123,2007
specific locus test hamster ovary 400 Ámol/L/20 minute MUREAV 602,14,2006
specific locus test mouse kidney 65 Ámol/L MUREAV 503,69,2002
specific locus test mouse Ascites tumor 5 mg/L/4 hour EMMUEG 42,19,2003


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
mouse
lowest published toxic dose: 144 gm/kg/26 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Gastrointestinal: Tumors
GANNA2 75,17,1984
oral
mouse
toxic dose : 168 gm/kg/30 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Gastrointestinal: Tumors
GANNA2 75,17,1984
skin
mouse
lowest published toxic dose: 4,032 mg/kg/18 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Skin and Appendages: Tumors

Tumorigenic: Facilitates action of known carcinogens
ARTODN 78,139,2004


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
human
lowest published toxic concentration: 10 mg/m3 Skin: After topical application: Primary irritation VCVN1* -,18,1998
inhalation
human
lowest published toxic concentration: 20 mg/m3 Peripheral Nerve and Sensation: Flaccid paralysis with appropriate anesthesia

Behavioral: Tetany

Cardiac: Arrythmias (indlucing changes in conduction)
VCVN1* -,18,1998
inhalation
mammal (species unspecified)
lowest published toxic concentration: 60 mg/m3/4 hour Skin: After topical application: Primary irritation VCVN1* -,17,1998
inhalation
mouse
lowest published lethal concentration: 227 ppm N/R AEHLAU 4,327,1962
inhalation
rat
lethal concentration (50 percent kill): 2 gm/m3/4 hour Lung, Thorax, or Respiration: Pulmonary emboli GTPZAB 21(10),22,1977
inhalation
rat
lethal concentration (50 percent kill): 2,000 mg/m3 N/R VCVN1* -,17,1998
intraperitoneal
mouse
lethal dose (50 percent kill): 880 mg/kg N/R VCVN1* -,17,1998
intravenous
dog
lowest published toxic dose: 0.3 mg/kg Behavioral: Excitement

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,17,1998
intravenous
horse, donkey
lowest published toxic dose: 40 Ág/kg Cardiac: Pulse rate increased without fall in BP

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Hypermotility, diarrhea
VCVN1* -,17,1998
intravenous
rabbit
lethal dose (50 percent kill): 15 gm/kg Behavioral: Convulsions or effect on seizure threshold MRLR** #75,1951
intravenous
rabbit
lowest published lethal dose: 0.4 mg/kg Behavioral: Tremor

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,17,1998
oral
mouse
lethal dose (50 percent kill): 2,000 mg/kg N/R VCVN1* -,17,1998
oral
rat
lethal dose (50 percent kill): 376 mg/kg Gastrointestinal: Peritonitis

Blood: Pigmented or nucleated red blood cells

Blood: Changes in leukocyte (WBC) count
STGNBT -,39,1999
oral
rat
lethal dose (50 percent kill): 4,050 mg/kg N/R VCVN1* -,17,1998
subcutaneous
mouse
lethal dose (50 percent kill): 1,072 mg/kg N/R GISAAA 48(6),28,1983
subcutaneous
rat
lethal dose (50 percent kill): 620 mg/kg N/R VCVN1* -,17,1998
skin
mammal (species unspecified)
lowest published toxic concentration: 110 mg/m3 Cardiac: Pulse rate increased without fall in BP

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,17,1998
skin
mouse
lethal dose (50 percent kill): 1,072 mg/kg N/R VCVN1* -,17,1998
skin
mouse
lowest published toxic concentration: 10 pph Vascular: Other changes VCVN1* -,18,1998
skin
pig
lowest published lethal dose: 2 gm/kg Behavioral: Convulsions or effect on seizure threshold MRLR** #75,1951
skin
rat
lethal dose (50 percent kill): 4,060 mg/kg Lung, Thorax, or Respiration: Pulmonary emboli GTPZAB 21(10),22,1977
skin
rat
lethal concentration (50 percent kill): 4,060 mg/m3 Lung, Thorax, or Respiration: Other changes

Biochemical: Effect on specific coenzyme: Disturbed regulation
VCVN1* -,17,1998
skin
rabbit
lowest published lethal dose: 500 mg/kg Behavioral: Convulsions or effect on seizure threshold MRLR** #75,1951
skin
rabbit
lowest published lethal concentration: 15 pph Eye: Lacrimation

Behavioral: Headache

Lung, Thorax, or Respiration: Cough
VCVN1* -,18,1998


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
dog
lowest published toxic concentration: 7 ppm/6 hour/26 week- intermittent Skin: After systemic exposure: Dermatitis, other

Skin and Appendages: Other: Hair
AMIHBC 10,319,1954
inhalation
mouse
lowest published toxic concentration: 57 ppm/6 hour/6 week- intermittent Skin: After systemic exposure: Dermatitis, irritative

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
AMIHBC 10,319,1954
inhalation
rat
lowest published toxic concentration: 67 ppm/6 hour/6 week- intermittent Skin: After systemic exposure: Dermatitis, irritative

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
AMIHBC 10,319,1954
inhalation
rat
lowest published toxic concentration: 10 mg/m3/5 hour/17 week- intermittent Lung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Monoamine oxidase

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases
GTPZAB 21(10),22,1977
inhalation
rat
lowest published toxic concentration: 10 mg/m3/5 hour/8 week- intermittent Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases VCVN1* -,18,1998
inhalation
rat
lowest published toxic concentration: 10 mg/m3/5 hour/17 week- intermittent Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
VCVN1* -,18,1998
intraperitoneal
non-mammalian species
lowest published toxic dose: 12 mg/kg/6 day- intermittent Liver: Other changes TOXID9 66,67,2002
oral
rat
lowest published toxic dose: 8.75 mg/kg/25 week- continuous Endocrine: Effect on menstrual cycle

Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VCVN1* -,19,1988
oral
rabbit
lowest published toxic dose: 8.75 mg/kg/25 week- continuous Endocrine: Effect on menstrual cycle

Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VCVN1* -,19,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 1 ppm DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed animal carcinogen DTLVS* TLV/BEI,2007
International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMEMDT 36,285,1985
International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMEMDT 71,671,1999
International Agency for Research on Cancer (IARC) Cancer Review Human No Adequate Data IMEMDT 36,285,1985
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 71,671,1999
International Agency for Research on Cancer (IARC) Cancer Review Group 3 IMEMDT 71,671,1999
TOXICOLOGY REVIEW
MUREAV 566,99,2004
TOXICOLOGY REVIEW
MUREAV 544,179,2003
TOXICOLOGY REVIEW
TXAPA9 197,144,2004
TOXICOLOGY REVIEW
FCTOD7 44,301,2006
TOXICOLOGY REVIEW
MUTAEX 19,251,2004
TOXICOLOGY REVIEW
MUREAV 616,11,2007
TOXICOLOGY REVIEW
ENTOX* -,543,2005
TOXICOLOGY REVIEW
MUREAV 635,90,2007
TOXICOLOGY REVIEW
MUTAEX 19,3,2004
TOXICOLOGY REVIEW
MUREAV 584,1,2005
TOXICOLOGY REVIEW
MUREAV 533,65,2003
TOXICOLOGY REVIEW
MUREAV 533,133,2003
TOXICOLOGY REVIEW
MUREAV 533,183,2003
TOXICOLOGY REVIEW
MUTAEX 19,169,2004
TOXICOLOGY REVIEW
MUREAV 658,154,2008
TOXICOLOGY REVIEW
MUTAEX 19,251,2004
TOXICOLOGY REVIEW
MUTAEX 19,251,2004
TOXICOLOGY REVIEW
MUREAV 659,15,2008
TOXICOLOGY REVIEW
REPTED 25,291,2007
TOXICOLOGY REVIEW
MUREAV 657,84,2008
TOXICOLOGY REVIEW
HUTOX* -,683,1996
TOXICOLOGY REVIEW
MUREAV 672,1,2009
TOXICOLOGY REVIEW
MUREAV 543,191,2003
TOXICOLOGY REVIEW
MUREAV 681,3,2009


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: RED Completed RBREV* -,330,1998
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 1 ppm (1.4 mg/m3) DTLVS* 3,131,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 1 ppm (1.4 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 1 ppm (1.4 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 1 ppm (1.4 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 1 ppm (1.4 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 1 ppm (1.4 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 1 ppm (1.4 mg/m3), MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 1 ppm (1.4 mg/m3), OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 1 ppm (1.4 mg/m3), short term exposure limit 3 ppm (4.2 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 1 ppm (1.5 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 0.71 mg/m3 (0.5 mL/m3), 2005
Occupational Exposure Limit - KOREA time-weighted average 1 ppm (1.5 mg/m3), 2006
Occupational Exposure Limit - MEXICO time-weighted average 1 ppm (1.5 mg/m3);
short term exposure limit 2 ppm (3 mg/m3), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 1.4 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 1 ppm (1.4 mg/m3), JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 1 ppm (1.4 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 1 ppm (1.4 mg/m3), JAN1993
Occupational Exposure Limit - SWEDEN time-weighted average 1 ppm (1.4 mg/m3), ceiling concentration 2 ppm (3 mg/m3), JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 0.5 ppm (0.71 mg/m3),KZG- week 0.5 ppm (0.71 mg/m3), DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 1 ppm (1.4 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 1 ppm (1.4 mg/m3);
short term exposure limit 2 ppm, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Confirmed animal carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Confirmed animal carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO HYDROGEN PEROXIDE-air 10 hour time-weighted average 1.0 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 38605;
Number of Industries 168;
Total Number of Facilities 19,597;
Number of Occupations 83;
Total Number of Employees Exposed 422,227
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 38605;
Number of Industries 171;
Total Number of Facilities 22,930;
Number of Occupations 142;
Total Number of Employees Exposed 1,006,752;
Total Number of Female Employees Exposed 727,702


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an industrial chemical, food and feed additive, flavor, packaging material
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8799
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961-
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ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
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HUTOX*
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Used as an industrial chemical, food and feed additive, flavor, packaging material

NIOSH PROFILE (HAIRDRESSING and BARBERS), SRC, 6/80

NIOSH PROFILE (PHOTOGRAPHIC PROCESSING), FIRL, 4/78

FDA-over the counter drug

RTECS Compound Description:
   Tumorigen
   Drug
   Mutagen
   Human Data
   Hormone
   Primary Irritant

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