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Cellulose

RTECS #: FJ5691460

CAS #: 9004-34-6


UPDATE: February 2009 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Abicel
  2. Arbocel
  3. Arbocel BC 200
  4. Arbocell B 600/30
  5. Avicel
  6. Avicel 101
  7. Avicel 102
  8. Avicel CL 611
  9. Avicel PH 101
  10. Avicel PH 105
  11. CEPO
  12. CEPO S 20
  13. CEPO S 40
  14. Cellex MX
  15. Cellulose (ACGIH:OSHA)
  16. Cellulose 248
  17. Cellulose crystalline
  18. Celufi
  19. Cepo CFM
  20. Chromedia CC 31
  21. Chromedia CF 11
  22. Cupricellulose
  23. Elcema F 150
  24. Elcema G 250
  25. Elcema P 050
  26. Elcema P 100
  27. Fresenius D 6
  1. Heweten 10
  2. Hydroxycellulose
  3. Kingcot
  4. LA 01
  5. MN - Cellulose
  6. Microcrystalline cellulose
  7. Onozuka P 500
  8. Pyrocellulose
  9. Rayophane
  10. Rayweb Q
  11. Rexcel
  12. Sigmacell
  13. Solka - floc BW 20
  14. Solka - floc BW 200
  15. Solka - floc BW 2030
  16. Solka - fil
  17. Solka - floc
  18. Solka - floc BW
  19. Solka - floc BW 100
  20. Spartose OM - 22
  21. Sulfite cellulose
  22. Tomofan
  23. Tunicin
  24. Whatman CC - 31
  25. alpha - Cellulose
  26. beta - Amylose


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lethal concentration (50 percent kill): >5,800 mg/m3/4 hour N/R TOLED5 (Suppl),243,1992
intraperitoneal
rat
lethal dose (50 percent kill): >31,600 mg/kg N/R FAONAU 50A,83,1972
oral
rat
lethal dose (50 percent kill): >5 gm/kg N/R TOLED5 (Suppl),243,1992
oral
rat
lowest published toxic dose: 120 gm/kg Gastrointestinal: Hypermotility, diarrhea

Gastrointestinal: Other changes
EPASR* #86940001000,1994
skin
rabbit
lethal dose (50 percent kill): >2 gm/kg N/R TOLED5 (Suppl),243,1992


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 420 gm/kg/4 week- continuous Gastrointestinal: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
AJPHAP 188,550,1957
oral
rat
lowest published toxic dose: 159 gm/kg/90 day- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain TOXID9 90,346,2006


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 mg/m3 DTLVS* TLV/BEI,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1915.1000,1993
Occupational Exposure Limit - BELGIUM time-weighted average 10 mg/m3, MAR2002
Occupational Exposure Limit - FRANCE VME 10 mg/m3, FEB2006
Occupational Exposure Limit - KOREA time-weighted average 10 mg/m3, 2006
Occupational Exposure Limit - MEXICO time-weighted average 10 mg/m3;
short term exposure limit 20 mg/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 2 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 10 mg/m3 (inspirable dust), JAN2002
Occupational Exposure Limit - RUSSIA short term exposure limit 10 mg/m3, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 3 mg/m3, DEC2006
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 4 mg/m3;
short term exposure limit 20 mg/m3 (respirable), 2005
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 10 mg/m3 (inhalable), 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 10 mg/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 10 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CELLULOSE, respirable fraction-air 10 hour time-weighted average 5 mg/m3 NIOSH* DHHS #95-121,1995
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CELLULOSE, total dust-air 10 hour time-weighted average 10 mg/m3 NIOSH* DHHS #95-121,1995


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as binders, thickeners, disintegrates in drug and food industry
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

AJPHAP American Journal of Physiology. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1898-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown.
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-

Used as binders, thickeners, disintegrates in drug and food industry

ALT CAS #: 9006-02-4
ALT CAS #: 39394-43-9
ALT CAS #: 58968-67-5
ALT CAS #: 61991-21-7
ALT CAS #: 61991-22-8
ALT CAS #: 84503-75-3
ALT CAS #: 99331-82-5
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