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Bacillus subtilis carlsberg

RTECS #: CO9550000

CAS #: 9014-01-1


UPDATE: May 2009 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. ALK - enzyme
  2. Alcalase
  3. Bacillopeptidase A
  4. Bacillopeptidase B
  5. Bioprase
  6. Colistinase
  7. E.C. 3.4.21.14
  8. E.C. 3.4.4.16
  9. Maxatase
  10. Nagarse
  11. SP 266
  1. Subtilisin (9CI)
  2. Subtilisin (ACGIH)
  3. Subtilisin NOVO
  4. Subtilisin bpn'
  5. Subtilisin carlsburg
  6. Subtilisins
  7. Subtilopeptidase A
  8. Subtilopeptidase B
  9. Subtilopeptidase C
  10. Subtilopeptidase bpn'
  11. Thermoase PC - 10


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
3 mg moderate FCTXAV 7,581,1969


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intratracheal
guinea pig
lowest published toxic dose: 20 g/kg Immunological Including Allergic: Increase in humoral response TOXID9 60,175,2001
oral
rat
lethal dose (50 percent kill): 3,700 mg/kg N/R FCTXAV 7,581,1969


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lowest published toxic concentration: 0.1 pph/3 day- intermittent Lung, Thorax, or Respiration: Other changes

Immunological Including Allergic: Increase in humoral response
TOXID9 60,10,2001


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value ceiling concentration 0.00006 mg/m3 DTLVS* TLV/BEI,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.0003 mg/m3 DTLVS* 3,236,1971
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.00006 mg/m3, JUL2008
Occupational Exposure Limit - DENMARK ceiling concentration 0.00006 mg/m3, OCT 2002
Occupational Exposure Limit - MEXICO peak 0.00006 mg/m3, 2004
Occupational Exposure Limit - NEW ZEALAND ceiling concentration 0.00006 mg/m3, sen, JAN2002
Occupational Exposure Limit - SWEDEN time-weighted average 1 glycine unit/m3, ceiling concentration 3 glycine unit/m3, Sen, JUN2005
Occupational Exposure Limit - SWITZERLAND KZG- week 0.00006 mg/m3, DEC2006
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.00004 mg/m3 (sen), 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

ceiling concentration 0.00006 mg/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
ceiling concentration 0.00006 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SUBTILISINS-air short term exposure limit 0.00006 mg/m3/60 minute NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X1796;
Number of Industries 3;
Total Number of Facilities 225;
Number of Occupations 5;
Total Number of Employees Exposed 5,548;
Total Number of Female Employees Exposed 1,814


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8800
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-

RTECS Compound Description:
   Natural Product
   Primary Irritant

Click Here for Additional Information about RTECS

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