An illness with a) discrete onset of symptoms and b) jaundice or
elevated serum aminotransferase levels
Laboratory criteria for diagnosis
Hepatitis A: IgM anti-HAV-positive
Hepatitis B: IgM anti-HBc-positive (if done) or HBsAg-positive,
and IgM anti-HAV-negative (if done)
Non-A, Non-B Hepatitis:
IgM anti-HAV-negative, and
IgM anti-HBc-negative (if done) or HBsAg-negative, and
Serum aminotransferase levels greater than 2 1/2 times
the upper limit of normal
Delta Hepatitis: HBsAg- or IgM anti-HBc-positive
and anti-HDV-positive
Case classification
Confirmed: a case that meets the clinical
case definition and is laboratory confirmed
Comment
A serologic test for IgG antibody to the recently described hepatitis
C virus is available, and many cases of non-A, non-B hepatitis may be demonstrated
to be due to infection with the hepatitis C virus. With this assay, however, a
prolonged interval between onset of disease and detection of antibody may occur.
Until a more specific test for acute hepatitis C becomes available, these cases
should be reported as non-A, non-B hepatitis. Chronic carriage or chronic hepatitis
should not be reported.