CDC has expanded the acquired immunodeficiency syndrome (AIDS)
surveillance case definition to include all human immunodeficiency virus (HIV)-infected
adolescents and adults aged greater than or equal to 13 years who have either
a) less than 200 CD4positive T-lymphocytes/uL; b) a CD4positive T-lymphocyte percentage of total
lymphocytes of less than 14%; or c) any of the following three clinical conditions:
pulmonary tuberculosis, recurrent pneumonia, or invasive cervical cancer. The
expanded definition retains the 23 clinical conditions in the AIDS surveillance
case definition published in 1987. (See publication (1) in Publications List in
this section for complete information referring to this case definition.)
The AIDS surveillance case definition for children aged less
than 13 years has not changed and retains the clinical conditions listed in
the AIDS surveillance case definition published in 1987. However, definitions
for HIV encephalopathy, HIV wasting syndrome, and HIV infection in children
have been revised and the 1987 definition has been updated. (See Publication
(2) in Publications List for complete information pertaining to this case definition.)
Laboratory criteria for diagnosis
See Publication (1) in Publications List.
Case classification
CDC has revised the classification system for HIV infection to
emphasize the clinical importance of the CD4positive T-lymphocyte count in the categorization
of HIV-related clinical conditions. This classification system replaces the system
published by CDC in 1986. (See Publication (1) in Publications List for complete
information pertaining to this case definition.)
Publications list
CDC. 1993 Revised classification system for HIV infection
and expanded surveillance case definition for AIDS among adolescents and adults.
MMWR 1992;41(No. RR-17).
CDC. 1994 Revised classification system for human immunodeficiency
virus infection in children less than 13 years of age. MMWR 1994;43(No.
RR-12).
CDC. Interpretation and use of the Western blot assay for
serodiagnosis of human immunodeficiency virus type-1 infection. MMWR
1989;38(No. S-7).
Revision of the CDC surveillance case definition for acquired
immunodeficiency syndrome. MMWR 1987;36(suppl:)1-15s.