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Pathologic Studies of Fatal Cases in Outbreak of Hand, Foot, and Mouth Disease, Taiwan

Wun-Ju Shieh,* Shih-Ming Jung,† Chuen Hsueh,† Tseng-Tong Kuo,† Anthony Mounts,* Umesh Parashar,* Chen Fu Yang,* Jeannette Guarner,* Thomas G. Ksiazek,* Jacqueline Dawson,* Cynthia Goldsmith,* Gwong-Jen J. Chang,* Steve M. Oberste,* Mark A. Pallansch,* Larry J. Anderson,* Sherif R. Zaki,* and the Epidemic Working Group (1)
*Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Chang Gung Memorial Hospital, Tauyuan, Taiwan, Republic of China

Figure 3. Age-specific incidence (per 100,000) and case-fatality ratio (percent) of invasive pneumococcal disease, Active Bacterial Core surveillance, 1998.

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Figure 1.  A). Positive immunostaining of EV71 antigens in neuron and neuronal process. Original magnification, X158. B). Positive immunostaining of EV71 antigens in necrotic area. Original magnification, X158. C). An array of picornavirus particles in a neuron (electron micrograph).
 

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This page last reviewed February 20, 2001

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National Center for Infectious Diseases
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