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Research

Lack of Evidence of Endogenous Avian Leukosis Virus and Endogenous Avian Retrovirus Transmission to Measles Mumps Rubella Vaccine Recipients

Althaf I. Hussain,* Vedapuri Shanmugam,* William M. Switzer,* Shirley X. Tsang,* Aly Fadly,† Donald Thea,‡ Rita Helfand,* William J. Bellini,* Thomas M. Folks,* and Walid Heneine*
*Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Avian Disease and Oncology Laboratory, U.S. Department of Agriculture, East Lansing, Michigan, USA; ‡Harvard Institute for International Development, Cambridge, Massachusetts, USA


Figure 1. Western blot antibody reactivity of chicken sera to endogenous avian leukosis virus (ALV) (Rous-associated virus 0) antigen. a) Lane 1, negative control chicken serum; Lane 2, positive control anti-p27 ALV gag antiserum; lanes 3-5, sera from ALV antibody-positive chickens; lanes 6-12, sera from ALV-negative, antibody-negative chickens.

Figure 1. Western blot antibody reactivity of chicken sera to endogenous avian leukosis virus (ALV) (Rous-associated virus 0) antigen. b) NC, negative control human sera; PC, positive control: anti-p27 ALV gag antiserum; lanes 1-10, sera from measles mumps rubella vaccine recipients.

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Figure 1. Western blot antibody reactivity of chicken sera to endogenous avian leukosis virus (ALV) (Rous-associated virus 0) antigen. a) Lane 1, negative control chicken serum; Lane 2, positive control anti-p27 ALV gag antiserum; lanes 3-5, sera from ALV antibody-positive chickens; lanes 6-12, sera from ALV-negative, antibody-negative chickens. b) NC, negative control human sera; PC, positive control: anti-p27 ALV gag antiserum; lanes 1-10, sera from measles mumps rubella vaccine recipients.
 


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