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Volume 4 No. 3 / July-September 1998 (1625 bytes)


 

Dispatches

An Outbreak of Hantavirus Pulmonary Syndrome, Chile, 1997

Jorge Toro,* Jeanette D. Vega,† ‡‡ Ali S. Khan,‡ James N. Mills,‡ Paula Padula,§ William Terry,‡ Zaida Yadón,§ Rosa Valderrama,¶ Barbara A. Ellis,‡ Carlos Pavletic,* Rodrigo Cerda,† Sherif Zaki,‡ Shieh Wun-Ju,‡ Richard Meyer,‡ Mauricio Tapia,# Carlos Mansilla,# Michel Baro,** Jose A. Vergara,** Marisol Concha,* Gladys Calderon,†† Delia Enria,†† C.J. Peters,‡ and Thomas G. Ksiazek‡
*Ministry of Health, Santiago, Chile; †Pan American Health Organization, Santiago, Chile; ‡Centers for Disease Control and Prevention, Atlanta, Georgia, USA; §Instituto Nacional de Enfermedades Infecciosas ANLIS "Carlos G. Malbran," Buenos Aires, Argentina; ¶Aysen Region XI Health Service, Coyhaique, Chile; #Coyhaique Regional Hospital, Coyhaique, Aysen, Chile; **Llanchipal Health Services, Puerto Montt, Chile; ††Instituto Nacional de Enfermedades Virales Humanas, Pergamino, Argentina; and ‡‡Catholic University of Chile, Santiago, Chile.


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Figure 1. Temporal distribution of hantavirus pulmonary syndrome cases, Chile, 1995-1998.


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Figure 2. Geographic distribution of hantavirus pulmonary syndrome cases, Chile, 1995-1998.


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Figure 3. Time-line listing for hantavirus pulmonary syndrome cases in Cluster 1, Chile, 1997.


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Figure 4. A) Low-power photomicrograph of lung showing interstitial pneumonitis and intraalveolar edema. B) Andes virus antigen–positive intraalveolar macrophages. C) Fine granular immunostaining of hantaviral antigens in endothelial cells of pulmonary microvasculature. (A, Hematoxylin and eosin; B,C, napthol-fast red with hematoxylin counterstain; original magnifications A x 50, B and C x 250.)

 

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