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Volume 4 No. 3 / July-September 1998 (1625 bytes)



Synopses

Chlamydia pneumoniae and Cardiovascular Disease

Lee Ann Campbell, Cho-Chou Kuo, and J. Thomas Grayston
University of Washington, Seattle, Washington, USA


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Figure 1. Ultrastructural evidence of Chlamydia pneumoniae in coronary atheroma. This transmission electron micrograph demonstrates the presence of endosomes containing C. pneumoniae pear-shaped elementary bodies within a foam cell in tissue from coronary artery atheroma. Arrows in inset point to the elementary bodies. Bar=0.5 µm. (Reprinted from Journal of Infectious Diseases (8) with permission from the publisher, University of Chicago Press).

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Figure 2. Immunocytochemical staining demonstrating Chlamydia pneumoniae in fibrolipid plaque from coronary artery atheroma. Panel A illustrates positive staining of foam cells in the plaque with the C. pneumoniae—specific monoclonal antibody TT-401. Panel B shows negative staining of the adjacent section using normal ascites fluid as the control.

 

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