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Figure. Amino acid alignment of the four chemokines was performed with the PC/Gene program. An overall identity and similarity of 12.4% and 40.2% was calculated, respectively. The initiator methionine contained within each sequence is removed in the processing of the chemokine. The SDF-1 form shown is the ß-form; the -form lacks the C-terminal amino acids RFKM, thus reducing the net charge to +9.
* = a perfectly conserved residue.
. = a conservative change.