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Division of Vector-Borne Infectious Diseases Dengue: Clinical Manifestations and Epidemiology

 
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Hypothesis on Pathogenesis of DHF (Part 4)

  • Infected monocytes release vasoactive mediators, resulting in increased vascular permeability and hemorrhagic manifestations that characterize DHF and DSS
It has been hypothesized that the infected monocytes release vasoactive mediators, resulting in the increased vascular permeability and hemorrhagic manifestations that characterize dengue hemorrhagic fever or dengue shock syndrome. It should be noted, however, that to date there are no data from viremia studies to confirm this hypothesis.

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