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Division of Vector-Borne Infectious Diseases Dengue: Clinical Manifestations and Epidemiology

 
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Replication and Transmission of Dengue Virus (Part 2)

 
5.  Second mosquito ingests virus with blood
 
6.  Virus replicates in mosquito midgut and other organs, infects salivary glands
 
7.  Virus replicates in salivary glands 
Image: Replication and Transmission of Dengue Virus
 

This slide represents the part of the transmission cycle that takes place within the mosquito.

  1. The mosquito ingests blood containing the virus.
  2. The virus replicates in the mosquito midgut, the ovaries, nerve tissue and fat body. It then escapes into the body cavity, and later infects the salivary glands.
  3. The virus replicates in the salivary glands and when the mosquito bites another human, the cycle continues.

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This page last reviewed February 13, 2002

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National Center for Infectious Diseases |
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