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These next two slides review the transmission cycle in more
detail. This slide represents the part of the transmission
cycle that takes place within the human body.
- The virus is inoculated into humans with the mosquito
saliva.
- The virus localizes and replicates in various target organs,
for example, local lymph nodes and the liver.
- The virus is then released from these tissues and spreads
through the blood to infect white blood cells and other
lymphatic tissues.
- The virus is then released from these tissues and circulates
in the blood.
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