Volume 9, Number 7, July 2003

Global Screening for Human Viral Pathogens

Norman G. Anderson,* John L. Gerin,† and N. Leigh Anderson‡
*Viral Defense Foundation, Kensington, Maryland, USA; †Georgetown University Medical Center, Rockville, Maryland, USA; and ‡Plasma Proteome Institute, Washington, D.C., USA

Figure. Schematic representation of a process for systematic discovery of human viruses. The basic process (left vertical series of steps) depends on physical isolation and shotgun sequencing to obtain sequences of frequent and rare viruses. A series of additional steps (right box) can be added to deplete known viruses at two levels, thereby enhancing sensitivity for novel agents.

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This page last reviewed May 30, 2003

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
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