Volume 9, Number 4, April 2003

Bacterial Resistance to Penicillin G by Decreased Affinity of Penicillin-Binding Proteins: A Mathematical Model

L. Temime,* P.Y. Boëlle,* P. Courvalin,† and D. Guillemot†
^*Institut National de la Santé et de la Recherche Médicale, Unité 444, Paris, France; and †Unité des Agents Antibactériens, Institut Pasteur, Paris, France

Figure 3. Simulated changes with time in the distribution of resistance levels in the meningococcal population, starting from a situation close to that of France in 2001, under (a) constant antibiotic treatment conditions (1 treatment/3 y) and (b) a frequency of treatment reduced by half (1 treatment/6 y).

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This page last reviewed September 30, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention