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Figure 3. Sensitivity analysis: vaccine efficacy. Effect of a
change in Human papillomavirus (HPV) vaccine efficacy on the cost
effectiveness of vaccination compared with current practice under varying
assumptions of vaccine immunity. The triangles represent a vaccine which
provides lifetime immunity to high-risk types of HPV. The circles represent
a vaccine which requires booster shots every 10 years to remain effective
(base-case assumption). The hatches represent a vaccine that requires
booster shots every 5 years to remain effective. The dashed lines indicate
the $50,000 and $100,000 per quality-adjusted life year cost-effectiveness
thresholds. The base-case value of 75% efficacy is indicated by the arrow.
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