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Figure 1. Flow chart of the different categories and flows considered
in our model system. For simplicity, we considered 1 type of treatment
when analyzing the effects of an increase in high-risk behavior and treatment
delay. When considering the effects of overall change in treatment strategy,
all categories and flows were included in the analysis. Abbreviations:
m, mortality (composed of background deaths for all categories,
and for persons in the chronic phase of infection, HIV-related deaths
are included); Rx, treatment; R, resistance; M, monotherapy; H, highly
active antiretroviral therapy (HAART). Color code for the categories'
encircling ovals: black (uninfected); purple (wild type); blue (monotherapy
resistant strain); green (HAART-resistant strain). Background code of
oval categories: no fill (untreated); tan (monotherapy); gray (HAART).
Code for the categories' encircling ovals: single, no staging (uninfected
and acutely infected); double, staged categories (persons in the chronic
phase).
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