Volume 11, Number 7, July 2005

Norovirus Recombination in ORF1/ORF2 Overlap

Rowena A. Bull,* Grant S. Hansman,† Leighton E. Clancy,*‡ Mark M. Tanaka,* William D. Rawlinson,*‡ and Peter A. White*
*University of New South Wales, Sydney, New South Wales, Australia; †University of Tokyo, Tokyo, Japan; and ‡Prince of Wales Hospital, Randwick, New South Wales, Australia

Figure 2. Similarity plot for Sydney 2212. The graph represents as a percentage the identity of the 2 putative parental strains, New Orleans/279 (black line) and Lordsdale (short dash), with the recombinant strain Sydney 2212. The window size was 100 bp with a step size of 10 bp. The site where the 2 parental strains have equal identity to the recombinant (i.e., where the lines cross) is the predicted site of recombination. By varying the window from 20 to 200 bp, the average recombination site was nucleotide 5081 with reference to Lordsdale. The percentage identity of Arg320 (long dash) to Sydney 2212 is also plotted. ORF, open reading frame.

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This page last reviewed June 8, 2005

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
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