Volume 11, Number 7, July 2005

Norovirus Recombination in ORF1/ORF2 Overlap

Rowena A. Bull,* Grant S. Hansman,† Leighton E. Clancy,*‡ Mark M. Tanaka,* William D. Rawlinson,*‡ and Peter A. White*
*University of New South Wales, Sydney, New South Wales, Australia; †University of Tokyo, Tokyo, Japan; and ‡Prince of Wales Hospital, Randwick, New South Wales, Australia

Figure 1. Phylogenetic analysis of the nucleotide sequences of capsid and polymerase regions of 9 identified recombinant norovirus genogroup II strains in relation to 26 known strains and prototype strains. The left tree analyzes the relationship of a 420-bp region of the 3´ end of the polymerase region. The right tree shows the relationship of 550 bp of the 5´ end of the capsid sequence. Suspected recombinants are underlined to emphasize their different phylogenetic groupings, and strains described in this study are represented in boldface. The percentage bootstrap values in which the major groupings were observed among 100 replicates are indicated. The branch lengths are proportional to the evolutionary distance between sequences and the distance scale, in nucleotide substitutions per position, is shown. The capsid clustering is shown in bold and is based on the classification of Vinjé et al. (23) (Table).

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This page last reviewed June 10, 2005

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention