Volume 11, Number 1, January 2005

Norovirus Transmission on Cruise Ship

Elmira T. Isakbaeva,* Marc-Alain Widdowson,*† R. Suzanne Beard,* Sandra N. Bulens,*† James Mullins,* Stephan S. Monroe,* Joseph Bresee,* Patricia Sassano,‡ Elaine H. Cramer,* and Roger I. Glass*
*Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Atlanta Research and Education Foundation, Atlanta, Georgia, USA; and ‡Bucks County Department of Health, Doylestown, Pennsylvania, USA

Figure 2. Phylogram of 9 norovirus sequence types detected in outbreaks on ship X, 4 reference sequences from GenBank, and the Farmington Hills virus. The tree is based on a 277-nucleotide region (region C) of the capsid gene and was created using uncorrected distances calculated by the DISTANCES program (Genetics Computer Group, Madison, WI) and was constructed by neighbor-joining using the GROWTREE program version 10.3 (Genetics Computer Group). Numbers in parenthesis indicate number of samples with the identical sequence detected in a given outbreak. Box highlights sequence types belonging to the Farmington Hills virus that are indistinguishable in region C. GenBank accession no. for reference strains include Bristol virus, X76716; Toronto virus, U02030; Hawaii virus, U07611; and Norwalk virus, M87661. Scale bar represents 10% divergence.

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This page last reviewed December 20, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention