Volume 10, Number 7, July 2004

Mice Susceptible to SARS Coronavirus

David E. Wentworth*†, Laura Gillim-Ross,* Noel Espina,* and Kristen A. Bernard*†
*New York Department of Health, Albany, New York, USA; and †State University of New York, Albany, New York, USA

Figure 2. Mice inoculated with severe acute respiratory syndrome–associated coronavirus showed decreased weight gain and developed neutralizing antibodies. A) Average percentage original weight for 2 to 5 mock-inoculated (gray line and solid squares) and 6 to 15 virus-inoculated (solid line and open circles) mice. Error bars represent 1 standard deviation. B) Neutralization titers reported as reciprocal of serum dilution for individual mock-inoculated (solid bars) and virus-inoculated (bars with hatched marks) mice at time of sacrifice. Lowest dilution tested was 1:20.

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This page last reviewed June 22, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention