Volume 10, Number 5, May 2004

Fatal Spotted Fever Rickettsiosis, Kenya

Jeremiah S. Rutherford,* Kevin R. Macaluso,† Nathaniel Smith,‡ Sherif R. Zaki,§ Christopher D. Paddock,§ Jon Davis,* Norman Peterson,* Abdu F. Azad,† and Ronald Rosenberg*
*United States Army Medical Research Unit, Nairobi, Kenya; †University of Maryland School of Medicine, Baltimore, Maryland, USA; ‡Kijabe African Inland Church Mission Hospital, Kijabe, Kenya; and §Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Figure 2. Immunohistochemical localization of spotted fever group rickettsial antigens in various tissues of a patient with fatal spotted fever rickettsiosis, by immunoalkaline phosphatase stain with naphthol phosphate–fast red substrate and hemotoxylin counterstain. Rickettsiae and rickettsial antigens (red) in Kupffer cells in liver (A), perivascular infiltrates in skin (B), and glomerular endothelium in kidney (C) (naphthol–fast red stain with hematoxylin counterstain; original magnifications x158).

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This page last reviewed April 20, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention