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Volume 10, Number 2, February 2004

Ultrastructural Characterization of SARS Coronavirus

Cynthia S. Goldsmith,* Kathleen M. Tatti,* Thomas G. Ksiazek,* Pierre E. Rollin,* James A. Comer,* William W. Lee,* Paul A. Rota,* Bettina Bankamp,* William J. Bellini,* and Sherif R. Zaki*
*Centers for Disease Control and Prevention, Atlanta, Georgia, USA

 
 
Figure 5A.
Figure 5B.
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Figure 5. Ultrastructural characteristics of a bronchial alveolar lavage (BAL) from a patient with severe acute respiratory syndrome. A) Infected cells from a BAL specimen, showing numerous cytoplasmic and extracellular virions (arrowheads). Note the region of double-membrane vesicles (arrow), a common feature of coronavirus-infected cells. B) At higher magnification, double-membrane vesicles (arrow) are shown to contain diffuse, granular material. Bars, 1 mm. Note: For a printable reproduction of this image, please see the PDF version.

 

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This page last reviewed March 2, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention