Volume 10, Number 11, November 2004

Evaluating Human Papillomavirus Vaccination Programs

Al V. Taira,* Christopher P. Neukermans,† and Gillian D. Sanders†‡
*Stanford School of Medicine, Stanford, California, USA; †Stanford University, Stanford, California, USA; and ‡Duke University, Durham, North Carolina, USA

Figure 2. A) Vaccine penetration scenario. Relationship between percentage of the population receiving the vaccine and the number of lifetime cervical cancer cases. The solid line represents a female-only vaccination strategy. The dashed line represents a strategy of vaccinating both sexes. The arrow indicates the base-case scenario of a female-only strategy with 70% penetration. B) Vaccine penetration scenario. Relationship between percentage of the population receiving the vaccine and program cost-effectiveness. The solid line represents the cost-effectiveness ($/quality-adjusted life-year [QALY]) of a female-only vaccination program compared to current practice. The dashed line represents the incremental cost-effectiveness of including male participants in a vaccine program compared to a female-only strategy. The arrow indicates the base-case scenario of a female-only program with 70% penetration. C) Vaccine efficacy scenario. Relationship between vaccine efficacy and the number of cohort lifetime cervical cancer cases. The solid line represents a female-only vaccination strategy. The dashed line represents a strategy of vaccinating both sexes. The arrow indicates the base-case scenario of a female-only strategy assuming 90% vaccine efficacy. D) Vaccine efficacy scenario. Relationship between vaccine efficacy and program cost-effectiveness. The solid line represents the cost-effectiveness ($/quality-adjusted life-year [QALY]) of a female-only vaccination program compared to current practice. The dashed line represents the incremental cost-effectiveness of including male participants in a vaccine program compared to a female-only strategy. The arrow indicates the base-case scenario of a female-only program at 90% vaccine efficacy.

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This page last reviewed October 22, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention