Volume 10, Number 10, October 2004

Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia

Charles Ben Beard,* Patricia Roux,† Gilles Nevez,‡ Philippe M. Hauser,§ Joseph A. Kovacs,¶ Thomas R. Unnasch,# and Bettina Lundgren**
*Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; †Saint-Antoine University Hospital, Paris, France; ‡University of Picardy, Amiens, France; §University Hospital of Lausanne, Lausanne, Switzerland; ¶National Institutes of Health, Bethesda, Maryland, USA; #University of Alabama at Birmingham, Birmingham, Alabama, USA; and **Hvidovre Hospital, Hvidovre, Denmark

Figure 3. A model for the evolution of tandem repeats in Pneumocystis jirovecii, for repeat patterns that have been identified to date. The number of repeats is indicated on the left. The specific pattern of repeats is indicated on the right. The numbers 1, 2, and 3 represent three different repeat types with sequence variation in the first and fourth nucleotides. The repeat patterns that were not identified in this study but are postulated to exist, on the basis of identified patterns, are boxed. Solid arrows indicate potential evolution between isolates that have been identified, and dashed arrows indicate evolution between postulated isolates. Reprinted from (33) with permission from the University of Chicago Press.

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This page last reviewed September 21, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention