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Boldface

Avoid using boldface for emphasis in running text. Boldface may be used judiciously in tables, if necessary, to highlight significant values or isolates described in a given study, for example. Similar uses are permitted in figures. Usage should be defined in table footnote or figure legend (i.e., "Boldface indicates a significant result.").

Italics

  • Do not use italics for emphasis.
  • For use of italics with organisms, see Scientific Nomenclature.
  • Do not italicize coined terms. If necessary, set off in quotation marks at first occurrence only.
  • Single-letter variables are italicized. However, R0 (basic reproductive number) is not italicized to avoid confusion with R (correlation coefficient in multivariate analysis).
  • Do not use italics to format article headings, subheadings, table titles, or figure legends.
  • Do not use italics in keywords.
  • Do not italicize titles of books or journals, either in text or in references.
  • Italicize reference numbers in text but not in reference list.
  • Commas, colons, and semicolons that immediately follow italicized text should not be italicized.
  • Use the format p = 0.05 or p>0.05 (lowercase p, no italics; put zero before decimal, note spaces around =, no spaces around > and <).
  • Some foreign words and phrases have become part of standard English usage and do not need to be italicized, unless not using italics would be confusing. These terms include:

in vivo
in vitro
in situ
falciparum (in falciparum malaria)
et al.

Underlining

Do not underline for emphasis or to indicate book or journal titles. Do not underline URLs or email addresses. Underlining may be used to indicate nucleotide or amino acid substitutions.

Comments to the EID Editors

Please contact the EID Editors at eideditor@cdc.gov

The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.

This page posted January 29, 2009
This page last reviewed August 12, 2009

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