Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

NCHHSTP Newsroom
Your Connection to the Latest HIV/AIDS, Hepatitis, STD and TB News at CDC

Media Summary

Update to CDC’s Sexually Transmitted Diseases Treatment 2010 Guidelines: Oral Cephalosporins No Longer a Recommended Treatment for Gonococcal Infections

In light of recent laboratory data showing the oral antibiotic cefixime is becoming less effective, CDC has updated its STD Treatment Guidelines to no longer recommend the drug as a first-line treatment option for gonorrhea in the United States. This change leaves only one drug proven effective for treating infection, an injectable antibiotic called ceftriaxone. Over time gonorrhea has developed resistance to every antibiotic recommended, leaving the cephalosporins, which include cefixime and ceftriaxone, as the final recommended class of drugs. Because of this history and recent lab data, CDC is concerned that continued use of cefixime may prompt resistance to all cephalosporins. Limiting its use now may help preserve ceftriaxone as a treatment option for a little longer. Today, the most effective treatment for gonorrhea is dual therapy: ceftriaxone with another antibiotic. The guidelines outline alternative treatment options when ceftriaxone cannot be used. To closely monitor for resistant infections, the guidelines advise on follow-up testing using culture-based tests. Treating gonorrhea with the most effective method may help delay the emergence of cephalosporin resistance, but it will not solve the problem. CDC is calling on public and private partners to prioritize preventing gonorrhea and developing new treatment options.

Media Contact:
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention
News Media Line - 404-639-8895



Media Inquiries:
HIV/AIDS, Hepatitis, STDs or TB
  • (404) 639-8895
    M-F 9am-5:30pm (ET)
  • Email

All Other Topics

Public Inquiries:
  • Centers for Disease Control and Prevention
    1600 Clifton Rd
    Atlanta, GA 30333
  • 800-CDC-INFO
    TTY: (888) 232-6348

  • Contact CDC–INFO

The NCHHSTP Atlas is an interactive tool that provides CDC an effective way to disseminate HIV, Viral Hepatitis, STD and TB data, while allowing users to observe trends and patterns by creating detailed reports, maps, and other graphics. Find out more!

Prevention Through Health Care

May 19. HEPATITIS TESTING DAY.  Click here to learn more.

CDC 24/7 – Saving Lives. Protecting People. Saving Money Through Prevention. Learn More About How CDC Works For You The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Road Atlanta, GA 30329-4027, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO
A-Z Index
  1. A
  2. B
  3. C
  4. D
  5. E
  6. F
  7. G
  8. H
  9. I
  10. J
  11. K
  12. L
  13. M
  14. N
  15. O
  16. P
  17. Q
  18. R
  19. S
  20. T
  21. U
  22. V
  23. W
  24. X
  25. Y
  26. Z
  27. #