Outbreak Investigations

Dr. Rachel Slayton (CDC) collecting a water sample from a shallow well in Harare, Zimbabwe, 2012

Outbreak investigations, which CDC calls "Epi-Aids," result from requests for epidemiological assistance within the United States and throughout the world. Requests to assist with emergency responses, investigate infectious and environmental disease outbreaks, and quantify impact of diseases are examples of these responses.

Our global investigations are conducted in collaboration with international partners, such as ministries of health and the World Health Organization, as well as CDC's Global Disease Detection and Emergency Response program.

The investigations below include the Epi-Aid number, the way all Epi-Aids are tracked by CDC. When available, investigations also include articles and information published in the Morbidity and Mortality Weekly Report (MMWR) and on CDC web pages.

Waterborne Disease Prevention Branch Investigations

2012

Investigation of a multi-state outbreak of eye infections caused by Acanthamoeba in CDC's Emergency Operations Center, 2011

Dr. Julia Gargano (CDC) develops a survey sampling frame following a community water emergency in Alabama, 2010

• Naegleria fowleri infection – Saint Thomas, U.S. Virgin Islands
  • December 2012 (Epi-Aid 2013-022)
• Outbreak of cholera – Sierra Leone
  • August 2012 (Epi-Aid 2012-074)
• Outbreak of Guinea Worm Disease – Chad
  • April 2012 (Epi-Aid 2012-041)
• Outbreak of typhoid fever – Lusaka, Zambia
  • March 2012 (Epi-Aid 2012-034)

2011

• Outbreak of typhoid fever – Harare, Zimbabwe
  • December 2011 (Epi-Aid 2012-024)
  • MMWR: Notes from the field: Salmonella typhi infections associated with contaminated water—Zimbabwe, October 2011-May 2012
  • CDC web page: International Outbreak Investigations: Investigating Typhoid Fever in Zimbabwe
• Outbreak of typhoid fever characterized by intestinal perforations – Kasese and Bundibugyo Districts, Uganda
  • October 2011 (Epi-Aid 2012-009)
• Assessment of cholera mortality at hospitals and cholera treatment centers – Haiti
  • August 2011 (Epi-Aid -2011-085)
• Diarrheal incidence in United States healthcare personnel working with cholera patients in Haiti – United States, March-June 2011
  • June 2011 (Epi-Aid 2011-044)
• Nationwide persistence of Acanthamoeba keratitis (AK) cases above baseline following an AK outbreak in 2007 – United States, New York
  • March 2011 (Epi-Aid 2011-042)
  • CDC web page: 2011 Acanthamoeba Keratitis Investigation

2010

CDC scientist conducting epidemiologic study on water, sanitation and hygiene. Port-au-Prince, Haiti, 2010

• Outbreak of cholera – Haiti
  • October 2010 (Epi-Aid 2011-012)—as part of a CDC-wide team working in CDC's Emergency Operations Center
  • Emerging Infectious Diseases: Cholera in Haiti
  • MMWR: Update: outbreak of cholera—Haiti, 2010
  • MMWR: Update: cholera outbreak—Haiti, 2010
  • MMWR: Cholera outbreak—Haiti, October 2010
• Acanthamoeba keratitis infections among patients referred to Hospital A ophthalmologists – Georgia
  • October 2010 (Epi-Aid 2011-08)
• Outbreak of cholera – Cameroon
  • September 2010 (Epi-Aid 2010-097)
• Evaluation of the Niger national dracunculiasis eradication program – Niger
  • September 2010 (Epi-Aid 2010-096)
• Organ transplant-associated transmission of Balamuthia mandrillaris – Arizona
  • September 2010 (Epi-Aid 2010-094)—in conjunction with CDC's Division of Healthcare Quality Promotion
  • MMWR: Notes from the field: Transplant-transmitted Balamuthia mandrillaris—Arizona, 2010
• Acanthamoeba contamination of corneal transplant tissues from an eye bank – United States
  • August 2010 (Epi-Aid 2010-091)—in conjunction with CDC's Division of Healthcare Quality Promotion
• Health impact and emergency response assessment after disruption of water service – Alabama
  • February 2010 (Epi-Aid 2010-039)—in conjunction with CDC's National Center for Environmental Health
  • MMWR: Community health impact of extended loss of water service—Alabama, January 2010
• Transplant-associated transmission of Balamuthia mandrillaris – Mississippi and Kentucky, 2009-2010
  • January 2010 (Epi-Aid 2010-034)—in conjunction with CDC's Division of Healthcare Quality Promotion
  • MMWR: Balamuthia mandrillaris transmitted through organ transplantation—Mississippi, 2009

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