Name of Session
Session C 1
Exposure Biomarkers: Apples or Oranges
Description of Session
Because they are an unequivocal measure of exposure, biomarkers are a valuable tool for assessing human exposure to environmental chemicals. In CDC’s Third National Report on Human Exposure to Environmental Chemicals, they are used to track trends in the chemical exposure of the US population over time. However, interpreting these biomarkers at the individual level is problematic. What does the number mean and how well does it characterize the exposure of interest? How can we use it to inform us about toxicokinetics of the chemical and subsequent progression to disease? This session’s speakers will discuss four different chemical groups and how the relevant biomarkers are interpreted in the context of the exposure sources and the metabolic pathway of the compounds. The discussion will focus on the parameters that influence sampling strategies and the interpretation of specific biomarkers to promote better understanding of chemical body burdens.
| Presenter(s) | |
|---|---|
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Moderator: Susan W. Metcalf, MD | smetcalf@cdc.gov |
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Presenter 1: Stephen Rappaport, PhD | smr@unc.edu |
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Presenter 2: Don Patterson, PhD | DPatterson@cdc.gov |
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Presenter 3: Andreas Sjodin, PhD | ASjodin@cdc.gov |
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Presenter 4: Ketna Mistry, MD | KMistry@cdc.gov |


