Training & Education - Clincial FeaturesSummary
- The iron accumulation rate and the frequency and severity of clinical symptoms vary widely and may be dependent on factors such as age, gender, and diet.
- The most commonly associated early hemochromatosis symptoms are non-specific and may include:
- Weight loss.
- Abdominal pain.
- As iron accumulation progresses, patients may also experience:
- Symptoms of gonadal failure.
- For example, amenorrhea, early menopause, loss of libido, impotence.
- Shortness of breath/dyspnea.
- Maintain a high index of suspicion of hemochromatosis for patients with early signs or symptoms of this disease.
- Iron accumulates in the parenchymal cells of several organs; the liver is a major site followed by the heart and pancreas.
- The liver is usually the first organ to be affected, but signs of organ damage occur in the later stages of the disease.
Primary Disorders Associated with Advanced Hemochromatosis
- Most advanced hemochromatosis complications are also common primary disorders.
- A hemochromatosis diagnosis can be missed even in advanced stages unless looked for specifically.
This is an optional self-quiz and is not required for continuing education credit.
Select the best answers below. If you need help, feel free to go back to Clinical Expression and review.
- Centers for Disease Control and Prevention
National Center on Birth Defects and Developmental Disabilities
Division of Blood Disorders
1600 Clifton Road
Atlanta, GA 30333
TTY: (888) 232-6348
- Contact CDC-INFO