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Appendix B: Additional Articles on Vitamin B12 Deficiency

Allen R, Lindenbaum J, Stabler S. High prevalence of cobalamin deficiency in the elderly. Trans Am Clin Climatol Assoc. 1995;107:37–45.

Carmel R, Melnyk S, James J. Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism. Blood. 2003;101:3302–8.

Carmel R. Pernicious anemia: the expected findings of very low cobalamin levels, anemia, and macrocytosis are often lacking. Arch Intern Med. 1988;148:1712–4.

Clarke R. Prevention of vitamin B-12 deficiency in old age. Am J Clin Nutr. 2001;73:151–2.

Fairfield K, Fletcher R. Vitamins for chronic disease prevention in adults - Scientific Review. JAMA. 2002;287:3116–26.

Fletcher R, Fairfield K. Vitamins for chronic disease prevention in adults - clinical applications. JAMA. 2002;287:3127–9.

Herbert V. Vitamin B12 and folic acid supplementation. Am J Clin Nutr. 1997;66:1479–80.

Herrmann W, Schorr H, Bodis M, Knaapp J, Muller A, Stein G, et al. Role of homocysteine, cystathionine and methylmalonic acid measurement for the diagnosis of vitamin deficiency in high-aged subjects. Eur J Clin Invest. 2000;30:1083–9.

Ho G, Kauwell G, Bailey L. Practitioners’ guide to meeting the vitamin B12 recommended dietary allowances for people aged 51 years and older. J Am Diet Assoc. 1999;99:725–7.

Holleland G, Schneede J, Ueland P, Lund P, Refsum H, Sandberg S, et al. Cobalamin deficiency in general practice: assessment of the diagnostic utility and cost-benefit analysis of methylmalonic acid determination in relation to current diagnostic strategies. Clin Chem. 1999;45:189–98.

Hvas A, Ellegaard J, Nexo E. Increased plasma methylmalonic acid level does not predict clinical manifestations of vitamin B12 deficiency. Arch Intern Med. 2001;161:1535–41.

Johnson M, Hawthorne N, Brackett W, Fischer J, Gunter E, Allen R, et al. Hyperhomocysteinemia and vitamin B12 deficiency in elderly using title IIIC nutrition services. Am J Clin Nutr. 2003;77:211–20.

Lokk J, Nilsson M, Norberg B, Hultdin J, Sandstrom H, Westman G. Shifts in B12 opinions in primary health care of Sweden. Scand J Public Health. 2001;29:122–8.

Malouf R, Areosa S. Vitamin B12 for cognition. Cochrane Database Syst Rev. 2003:3.

Meins W, Muller-Thomsen T, Meier-Baumgartner H. Subnormal serum vitamin B12 and behavioral and psychological symptoms in Alzheimer’s disease. Int J Geriatr Psychiatry. 2000;15:415–8.

Misra U, Kalita J, Das A. Vitamin B12 deficiency neurological syndromes: a clinical, MRI, and electrodiagnostic study. Electromyogr Clin Neurophysiol. 2003;43:57–64.

Mitchell S, Rockwood K. The association between antiulcer medication and initiation of cobalamin replacement in older persons. J Clin Epidemiol. 2001;54:531–4.

Naurath H, Joosten E, Riezler R, Stabler S, Allen R, Lindenbaum J. Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. Lancet. 1995;346:85–9.

Penninx BW, Guralnick JM, Ferrucci L. Fried LP, Allen R, Stabler S. Vitamin B(12) deficiency and depression in physically disabled older women: epidemiologic evidence from the Women’s Health and Aging Study. Am J Psychiatry. 2000;157:715–21.

Stopeck A. Links between helicobacter pylori infection, cobalamin deficiency, and pernicious anemia. Arch Intern Med. 2000;160:1229–30.

Tiemeier H, van Tuiji H, Hoffman A, Meijer J, Kilaan A, Breteler M. Vitamin B12, folate, and homocysteine in depression: the Rotterdam Study. Am J Psychiatry. 2002;159:2099–101.

van Asselt D, Blom H, Zuiderent R, Wevers R, Jakobs C, van den Broek W, et al. Clinical significance of low cobalamin levels in older hospital patients. Neth J Med. 2000;57:41–9.

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